Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SELP | P16109 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | P2RY10 | O00398 | 4/20 | 0.38 |
| ▸ | GPR174 | Q9BXC1 | 3/20 | 0.38 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.38 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.35 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.35 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.35 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18541838 | 1.00 | SMN1; SMN2 (0.44) | SMN1; SMN2SELPPPARDP2RY10GPR174 | |
| SCHEMBL46668 | 1.00 | SMN1; SMN2 (0.44) | SMN1; SMN2SELPPPARDP2RY10GPR174 | |
| Ammonia Solution, Strong SCHEMBL28136552 | 0.98 | SMN1; SMN2 (0.42) | SMN1; SMN2SELPPPARDP2RY10GPR174 | |
| Diethyl Hydrogen Phosphate SCHEMBL16180713 | 0.90 | PPARD (0.45) | SMN1; SMN2SELPPPARDLPAR5LMNA | |
| SCHEMBL29708086 | 0.89 | SMN1; SMN2 (0.46) | SMN1; SMN2SELPP2RY10GPR174GPR34 | |
| SCHEMBL30148756 | 0.89 | SMN1; SMN2 (0.46) | SMN1; SMN2SELPP2RY10GPR174GPR34 | |
| SCHEMBL579431 | 0.89 | SMN1; SMN2 (0.46) | SMN1; SMN2SELPP2RY10GPR174GPR34 | |
| SCHEMBL12284729 | 0.89 | SMN1; SMN2 (0.46) | SMN1; SMN2SELPP2RY10GPR174GPR34 | |
| SCHEMBL24111174 | 0.87 | SMN1; SMN2 (0.44) | SMN1; SMN2SELPP2RY10GPR174GPR34 | |
| SCHEMBL12281973 | 0.87 | SMN1; SMN2 (0.44) | SMN1; SMN2SELPP2RY10GPR174GPR34 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8940907-B2 | Synthesis of phosphoric esters | MERCK PATENT GMBH (DE) | 2015-01-27 | — | — | US | disclosed |