Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | PKLR | P30613 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16418009 | 0.94 | BRD4 (0.45) | BRD4HTTALDH1A1SMN1; SMN2RECQL | |
| SCHEMBL9917426 | 0.90 | POLB (0.41) | BRD4HTTALDH1A1SMN1; SMN2RECQL | |
| SCHEMBL16418007 | 0.88 | BRD4 (0.48) | BRD4HTTALDH1A1SMN1; SMN2RECQL | |
| SCHEMBL9917433 | 0.84 | KCNH2 (0.42) | BRD4HTTALDH1A1SMN1; SMN2RECQL | |
| SCHEMBL9917344 | 0.78 | KCNH2 (0.49) | BRD4HTTALDH1A1SMN1; SMN2RECQL | |
| SCHEMBL16418006 | 0.75 | BRD4 (0.43) | BRD4HTTALDH1A1SMN1; SMN2RECQL | |
| SCHEMBL5530473 | 0.74 | RECQL (0.75) | BRD4HTTALDH1A1SMN1; SMN2RECQL | |
| SCHEMBL29459664 | 0.74 | RECQL (0.75) | BRD4HTTALDH1A1SMN1; SMN2RECQL | |
| SCHEMBL9917345 | 0.74 | KMO (0.52) | BRD4HTTALDH1A1SMN1; SMN2RECQL | |
| SCHEMBL9917337 | 0.74 | TP53 (0.51) | BRD4HTTALDH1A1SMN1; SMN2RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9149463-B2 | Methods and compositions of treating a Flaviviridae family viral infection | THE BOARD OF TRUSTEES OF THE LELAND STANDFORD JUNIOR UNIVERSITY (US) | 2015-10-06 | — | — | US | disclosed |
| US-8940730-B2 | Methods and compositions of treating a Flaviviridae family viral infection | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2015-01-27 | — | — | US | disclosed |