SCHEMBL16420337

SCHEMBL16420337

CCN1c2ccccc2N(c2cccc(N3c4ccccc4N(CC)[C@@H]3C)c2C)[C@@H]1C

nearest known ligand 0.32

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 2/20 0.32
▸ ALDH1A1 P00352 2/20 0.32
▸ GAA P10253 2/20 0.32
▸ HPGD P15428 2/20 0.32
▸ ALOX12 P18054 1/20 0.32
▸ GRIA1 P42261 2/20 0.31
▸ GRIA2 P42262 2/20 0.31
▸ GRIA3 P42263 2/20 0.31
▸ GRIA4 P48058 2/20 0.31
▸ GLA P06280 1/20 0.31
▸ POLB P06746 1/20 0.31
▸ MAPT P10636 1/20 0.31
▸ NPSR1 Q6W5P4 1/20 0.31
▸ L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16420312 0.90 GRIA1 (0.33) GRIA1GRIA2GRIA3GRIA4
SCHEMBL16421534 0.86 — —
SCHEMBL16727561 0.86 ELANE (0.38) KDM4EALDH1A1HPGDGRIA1GRIA2
SCHEMBL17131428 0.81 — —
SCHEMBL16420357 0.81 — —
SCHEMBL16525690 0.80 GRIA1 (0.38) KDM4EALDH1A1GAAHPGDALOX12
SCHEMBL17131789 0.78 GRIA1 (0.32) ALDH1A1ALOX12GRIA1GRIA2GRIA3
SCHEMBL16730318 0.77 PRKDC (0.32) —
SCHEMBL16420341 0.76 KDM4E (0.31) KDM4EALDH1A1GAAHPGDGLA
SCHEMBL16420322 0.76 KDM4E (0.47) KDM4EALDH1A1GAAHPGDALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10930866-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-02-23 — — US disclosed
US-20200176694-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-06-04 — — US disclosed
US-20170250354-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-08-31 — — US disclosed
US-20170250354-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-08-31 — — US disclosed
US-9748504-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2017-08-29 — — US disclosed
US-20150280146-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-10-01 — — US disclosed
US-20150028290-A1 HETEROLEPTIC OSMIUM COMPLEX AND METHOD OF MAKING THE SAME UNIVERSAL DISPLAY CORPORATION (US) 2015-01-29 — — US disclosed
US-20150028290-A1 HETEROLEPTIC OSMIUM COMPLEX AND METHOD OF MAKING THE SAME UNIVERSAL DISPLAY CORPORATION (US) 2015-01-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10930866-B2 Organic electroluminescent materials and devices OSBPL3, OR10J3, OSBP2 KDM4E 3560/4885ALDH1A1 1215/4885GAA 4541/4885
US-20150280146-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OXER1, SSB, RO60 KDM4E 2698/4885ALDH1A1 2401/4885GAA 3572/4885
US-20200176694-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OSBPL3, OR10J3, OSBP2 KDM4E 3560/4885ALDH1A1 1215/4885GAA 4541/4885
US-20170250354-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OSBPL3, OR10J3, OSBP2 KDM4E 3560/4885ALDH1A1 1215/4885GAA 4541/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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