⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17793323 | 0.76 | — | — | |
| SCHEMBL25794368 | 0.76 | ARG1 (0.37) | — | |
| SCHEMBL478031 | 0.70 | — | — | |
| SCHEMBL7385402 | 0.70 | — | — | |
| SCHEMBL25892555 | 0.70 | — | — | |
| SCHEMBL8021752 | 0.70 | — | — | |
| SCHEMBL17449732 | 0.68 | CYP3A4 (0.32) | — | |
| SCHEMBL12851469 | 0.68 | CYP3A4 (0.32) | — | |
| SCHEMBL5137869 | 0.68 | CYP3A4 (0.32) | — | |
| SCHEMBL41166 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170044214-A1 | SELECTIVE DELIVERY MOLECULES AND METHODS OF USE | AVELAS ACQUISITION CORPORATION | 2017-02-16 | — | — | US | disclosed |
| US-9278144-B2 | Selective delivery molecules and methods of use | AVELAS BIOSCIENCES, INC. (US) | 2016-03-08 | — | — | US | disclosed |
| US-20150031852-A1 | SELECTIVE DELIVERY MOLECULES AND METHODS OF USE | AVELAS BIOSCIENCES, INC. (US) | 2015-01-29 | — | — | US | disclosed |