⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10005840 | 1.00 | — | — | |
| SCHEMBL12674234 | 1.00 | — | — | |
| SCHEMBL12243052 | 0.92 | — | — | |
| SCHEMBL13998597 | 0.92 | — | — | |
| SCHEMBL12173555 | 0.92 | — | — | |
| SCHEMBL19768566 | 0.91 | IGF2R (0.35) | — | |
| SCHEMBL10005842 | 0.90 | — | — | |
| SCHEMBL1644129 | 0.90 | — | — | |
| SCHEMBL19608817 | 0.90 | — | — | |
| SCHEMBL13706079 | 0.89 | TLR4 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240067965-A1 | ORAL DELIVERY OF ANTISENSE CONJUGATES TARGETING PCSK9 | CIVI BIOPHARMA INC (US) | 2024-02-29 | — | — | US | disclosed |
| US-20230304014-A1 | MIRNA-485 INHIBITOR FOR HUNTINGTON'S DISEASE | BIORCHESTRA CO., LTD. (KR) | 2023-09-28 | — | — | US | disclosed |
| US-20230256119-A1 | COMPOSITIONS AND METHODS FOR PREPARING AN ALZHEIMER'S DISEASE ANIMAL MODEL USING MICRORNA | BIORCHESTRA CO., LTD. (KR) | 2023-08-17 | — | — | US | disclosed |
| US-11702652-B2 | Enzymatic encoding methods for efficient synthesis of large libraries | NUEVOLUTION A/S (DK) | 2023-07-18 | — | — | US | disclosed |
| US-20230167502-A1 | DIAGNOSTIC METHODS USING MIR-485-3P EXPRESSION | BIORCHESTRA CO., LTD. (KR) | 2023-06-01 | — | — | US | disclosed |
| US-20230126157-A1 | MIRNA-485 INHIBITOR FOR GENE UPREGULATION | BIORCHESTRA CO., LTD. (KR) | 2023-04-27 | — | — | US | disclosed |
| US-20180161356-A1 | TAU ANTISENSE OLIGOMERS AND USES THEREOF | ROCHE INNOVATION CENTER COPENHAGEN A/S (DK) | 2018-06-14 | — | — | US | disclosed |
| US-20180112217-A1 | Stereospecific Phosphorothioate LNA | ROCHE INNOVATION CENTER COPENHAGEN A/S (DK) | 2018-04-26 | — | — | US | disclosed |
| US-9885035-B2 | Method for the synthesis of a bifunctional complex | NUEVOLUTION A/S (DK) | 2018-02-06 | — | — | US | disclosed |
| US-9879265-B2 | Oligonucleotide conjugates | ROCHE INNOVATION CENTER COPENHAGEN A/S (DK) | 2018-01-30 | — | — | US | disclosed |
| US-20090264300-A1 | ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES | NUEVOLUTION A/S (DK) | 2009-10-22 | — | — | US | disclosed |
| US-20090239211-A1 | Method For Enrichment Involving Elimination By Mismatch Hybridisation | NUEVOLUTION A/S (DK) | 2009-09-24 | — | — | US | disclosed |
| US-20090202573-A1 | POLYMERIC CONJUGATES CONTAINING POSITIVELY-CHARGED MOIETIES | ENZON PHARMACEUTICALS, INC. (US) | 2009-08-13 | — | — | US | disclosed |
| US-20090203137-A1 | COMPOUNDS FOR THE MODULATION OF BETA-CATENIN EXPRESSION | SANTARIS PHARMA A/S (DK) | 2009-08-13 | — | — | US | disclosed |
| US-20090181916-A1 | LNA ANTAGONISTS TARGETING THE ANDROGEN RECEPTOR | SANTARIS PHARMA A/S (DK) | 2009-07-16 | — | — | US | disclosed |
| US-20090143232-A1 | METHOD FOR SYNTHESISING TEMPLATED MOLECULES | NUEVOLUTION A/S (DK) | 2009-06-04 | — | — | US | disclosed |
| US-20090118213-A1 | RNA ANTAGONIST COMPOUNDS FOR THE INHIBITION OF APO-B100 EXPRESSION | SANTARIS PHARMA A/S (DK) | 2009-05-07 | — | — | US | disclosed |
| US-7413854-B2 | Method for synthesising templated molecules | NUEVOLUTION A/S (DK) | 2008-08-19 | — | — | US | disclosed |
| US-20080188432-A1 | Short nucleotide subsequences located within number 15; such as locked nucleic acids antisense oligonucleotides; biostability, cell permeability; anticancer agents | SANTARIS PHARMA A/S (DK) | 2008-08-07 | — | — | US | disclosed |
| US-20070026397-A1 | Method for producing second-generation library | NUEVOLUTION A/S (DK) | 2007-02-01 | — | — | US | disclosed |