Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 1/20 | 0.31 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26029385 | 1.00 | TLR4 (0.31) | TLR4LY96CYP2C19HIF1A | |
| SCHEMBL10005840 | 0.89 | — | — | |
| SCHEMBL1642430 | 0.89 | — | — | |
| SCHEMBL12674234 | 0.89 | — | — | |
| SCHEMBL27104772 | 0.88 | TLR4 (0.30) | TLR4LY96 | |
| SCHEMBL26029373 | 0.88 | LY96 (0.34) | TLR4LY96 | |
| SCHEMBL8059872 | 0.85 | LGALS8 (0.34) | TLR4LY96CYP2C19HIF1A | |
| SCHEMBL26029389 | 0.85 | LGALS8 (0.34) | TLR4LY96CYP2C19HIF1A | |
| SCHEMBL19389554 | 0.85 | IGF2R (0.34) | TLR4LY96 | |
| SCHEMBL17520392 | 0.85 | IGF2R (0.34) | TLR4LY96 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109665-A1 | PHARMACEUTICAL COMPOSITIONS FOR TREATMENT OF MICRORNA RELATED DISEASES | SANTARIS PHARMA A/S (DK) | 2009-09-11 | — | — | WO | disclosed |