Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 2/20 | 0.41 |
| ▸ | MDM4 | O15151 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | PLK4 | O00444 | 1/20 | 0.37 |
| ▸ | PLK1 | P53350 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16426829 | 1.00 | CYP1A2 (0.49) | CYP1A2MAOBMAOAALPIPIM1 | |
| SCHEMBL16426716 | 0.83 | MAOB (0.48) | MAOBMAOAALPIPIM1PIM2 | |
| SCHEMBL16426717 | 0.83 | MAOB (0.48) | MAOBMAOAALPIPIM1PIM2 | |
| SCHEMBL28129799 | 0.82 | MAOB (0.43) | CYP1A2MAOBMAOAMAPT | |
| SCHEMBL16427343 | 0.73 | KDR (0.49) | MAOBMAOAALPIPIM1PIM2 | |
| SCHEMBL16427344 | 0.73 | KDR (0.49) | MAOBMAOAALPIPIM1PIM2 | |
| SCHEMBL13719529 | 0.72 | CYP1A2 (0.70) | CYP1A2MAOBMAOAALPIPIM1 | |
| SCHEMBL13719528 | 0.72 | CYP1A2 (0.70) | CYP1A2MAOBMAOAALPIPIM1 | |
| SCHEMBL5474689 | 0.70 | PLK4 (0.72) | CYP1A2PIM1TP53EGFRMAPT | |
| SCHEMBL16426515 | 0.70 | ELANE (0.43) | MAOBMAOAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150038543-A1 | ANTI-GLYCATION PROPERTIES OF OXINDOLE DERIVATIVES | CHOUDHARY MUHAMMAD IQBAL (PK) | 2015-02-05 | — | — | US | disclosed |