Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.48 |
| ▸ | CMA1 | P23946 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16426717 | 1.00 | MAOB (0.48) | MAOBCMA1AKR1C3AKR1C1MAOA | |
| SCHEMBL28129799 | 0.86 | MAOB (0.43) | MAOBMAOACYP19A1CYP11B2CYP11B1 | |
| SCHEMBL16427343 | 0.83 | KDR (0.49) | MAOBMAOAALPLALPIPIM1 | |
| SCHEMBL16427344 | 0.83 | KDR (0.49) | MAOBMAOAALPLALPIPIM1 | |
| SCHEMBL16426828 | 0.83 | CYP1A2 (0.49) | MAOBMAOAALPIPIM1PIM2 | |
| SCHEMBL16426829 | 0.83 | CYP1A2 (0.49) | MAOBMAOAALPIPIM1PIM2 | |
| SCHEMBL16426516 | 0.80 | ELANE (0.43) | MAOBMAOA | |
| SCHEMBL27755298 | 0.80 | MAPT (0.52) | MAOBMAOAPIM1PIM2 | |
| SCHEMBL16426515 | 0.80 | ELANE (0.43) | MAOBMAOA | |
| SCHEMBL16426758 | 0.77 | RAB9A (0.55) | MAOBMAOAPIM1PIM2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150038543-A1 | ANTI-GLYCATION PROPERTIES OF OXINDOLE DERIVATIVES | CHOUDHARY MUHAMMAD IQBAL (PK) | 2015-02-05 | — | — | US | disclosed |