⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL96070 | 0.80 | — | — | |
| SCHEMBL8237746 | 0.78 | LMNA (0.44) | — | |
| SCHEMBL2056168 | 0.77 | — | — | |
| SCHEMBL1580004 | 0.76 | LMNA (0.43) | — | |
| SCHEMBL2616802 | 0.76 | LMNA (0.43) | — | |
| SCHEMBL14677142 | 0.76 | LMNA (0.43) | — | |
| SCHEMBL314480 | 0.75 | — | — | |
| SCHEMBL3906075 | 0.75 | — | — | |
| SCHEMBL5808175 | 0.75 | — | — | |
| SCHEMBL5808177 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3523311-B1 | SUBSTITUTED 1H-IMIDAZO[4,5-B]PYRIDIN-2(3H)-ONES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2023-06-07 | — | — | EP | disclosed |
| EP-2487169-B1 | Compounds that inhibit (block) bitter taste in compositions and use thereof | SENOMYX INC (US) | 2015-05-20 | — | — | EP | disclosed |
| EP-2543667-B1 | A method of preparing 2-aminopyridine analogs as glucokinase activators | ARRAY BIOPHARMA INC (US) | 2015-01-28 | — | — | EP | disclosed |