Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.32 |
| ▸ | KRAS | P01116 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5841748 | 0.85 | AAK1 (0.37) | AAK1USP30PRMT5WDR77CYP2C9 | |
| SCHEMBL16426147 | 0.85 | PRMT5 (0.43) | AAK1USP30PRMT5WDR77BACE1 | |
| SCHEMBL31689032 | 0.81 | LIPE (0.37) | AAK1USP30PRMT5WDR77DGAT1 | |
| SCHEMBL6240652 | 0.81 | LIPE (0.37) | AAK1USP30PRMT5WDR77DGAT1 | |
| SCHEMBL16426109 | 0.79 | PRMT5 (0.43) | AAK1USP30PRMT5WDR77BACE1 | |
| SCHEMBL18532698 | 0.78 | AAK1 (0.37) | AAK1USP30PRMT5WDR77BACE1 | |
| SCHEMBL16429289 | 0.78 | CYP19A1 (0.34) | CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL2846997 | 0.76 | USP30 (0.38) | AAK1USP30PRMT5WDR77CYP2C9 | |
| SCHEMBL24770148 | 0.75 | USP30 (0.41) | AAK1USP30PRMT5WDR77CYP2C9 | |
| SCHEMBL31032180 | 0.75 | USP30 (0.41) | AAK1USP30PRMT5WDR77CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8962779-B2 | Method of forming polyaryl polymers | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-02-24 | — | — | US | disclosed |
| US-20150031847-A1 | METHOD OF FORMING POLYARYL POLYMERS | DOW GLOBAL TECHNOLOGIES LLC | 2015-01-29 | — | — | US | disclosed |