SCHEMBL16433142

SCHEMBL16433142

Cc1cc(O)cc2c1C(=O)c1c(O)ccc(O)c1C2=O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 4/20 0.53
MAPT P10636 8/20 0.51
MEN1 O00255 7/20 0.51
KMT2A Q03164 7/20 0.51
ALDH1A1 P00352 6/20 0.51
MAPK1 P28482 5/20 0.51
CYP3A4 P08684 4/20 0.51
TDP1 Q9NUW8 4/20 0.51
MAOA P21397 3/20 0.51
THRB P10828 3/20 0.51
ALOX15 P16050 3/20 0.51
CSNK2A2 P19784 3/20 0.51
CSNK2B P67870 3/20 0.51
CSNK2A1 P68400 3/20 0.51
CSNK2A3 Q8NEV1 3/20 0.51
APEX1 P27695 3/20 0.51
POLB P06746 3/20 0.51
TP53 P04637 2/20 0.51
HSD17B10 Q99714 2/20 0.51
PIM1 P11309 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28427769 0.93 LCK (0.50) ELANEMAPTMEN1KMT2AALDH1A1
SCHEMBL17867367 0.83 MAPT (0.73) ELANEMAPTMEN1KMT2AALDH1A1
SCHEMBL30800495 0.83 MAPT (0.73) ELANEMAPTMEN1KMT2AALDH1A1
SCHEMBL29596527 0.83 ELANE (0.67) ELANEMAPTMEN1KMT2AALDH1A1
SCHEMBL29596416 0.83 ELANE (0.67) ELANEMAPTMEN1KMT2AALDH1A1
SCHEMBL16432715 0.83 ELANE (0.67) ELANEMAPTMEN1KMT2AALDH1A1
SCHEMBL9175356 0.82 BCL2 (0.69) ELANEMAPTMEN1KMT2AALDH1A1
SCHEMBL26187341 0.81 BCL2 (0.68) ELANEMAPTMEN1KMT2AALDH1A1
SCHEMBL31433378 0.80 ESR2 (0.64) ELANEMAPTMEN1KMT2AALDH1A1
SCHEMBL15676184 0.79 ESR1 (0.47) ELANEMAPTMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11421223-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2022-08-23 US disclosed
US-20210309860-A1 ANTHRAQUINONIC DERIVATIVES AND THEIR USE AS COLOURING AGENTS PILI (FR) 2021-10-07 US disclosed
WO-2020016245-A1 ANTHRAQUINONIC DERIVATIVES AND THEIR USE AS COLOURING AGENTS PILI (FR) 2020-01-23 WO disclosed
US-20190309289-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2019-10-10 US disclosed
US-10370654-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2019-08-06 US disclosed
US-20180320170-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2018-11-08 US disclosed
US-9944925-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. 2018-04-17 US disclosed
US-20160186168-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. 2016-06-30 US disclosed
EP-3027754-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING enEvolv, Inc. (US) 2016-06-08 EP disclosed
WO-2015017866-A1 PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING ENEVOLV, INC. (US) 2015-02-05 WO disclosed