SCHEMBL16433754

SCHEMBL16433754

c1ccc(-c2c3ccccc3c(-c3ccccc3)c3cc(-c4cccc(-c5cc6cccnc6c6ncccc56)c4)ccc23)cc1

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 3/20 0.43
CCR8 P51685 3/20 0.43
L3MBTL1 Q9Y468 3/20 0.43
PIK3CD O00329 1/20 0.42
ALDH1A1 P00352 2/20 0.39
MAPT P10636 1/20 0.39
PDE4A P27815 1/20 0.39
CYP11B1 P15538 1/20 0.38
MEN1 O00255 1/20 0.38
LMNA P02545 1/20 0.38
HPGD P15428 1/20 0.38
KMT2A Q03164 1/20 0.38
CYP2C9 P11712 6/20 0.38
TOP1 P11387 2/20 0.38
ESR1 P03372 2/20 0.36
ESR2 Q92731 2/20 0.36
CCR5 P51681 1/20 0.36
BRD4 O60885 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16558125 0.96 CCR1 (0.44) CCR1CCR8L3MBTL1PIK3CDALDH1A1
SCHEMBL10300884 0.96 CCR1 (0.46) CCR1CCR8L3MBTL1PIK3CDALDH1A1
SCHEMBL12577947 0.94 PIK3CD (0.41) CCR1CCR8L3MBTL1PIK3CDALDH1A1
SCHEMBL12577893 0.90 PIK3CD (0.40) CCR1CCR8L3MBTL1PIK3CDALDH1A1
SCHEMBL12577902 0.89 CYP11B1 (0.43) CCR1CCR8L3MBTL1PIK3CDALDH1A1
SCHEMBL15977784 0.88 BRD4 (0.47) CCR1CCR8L3MBTL1PIK3CDALDH1A1
SCHEMBL12577888 0.88 CYP11B1 (0.42) CCR1CCR8L3MBTL1PIK3CDALDH1A1
SCHEMBL15977893 0.88 CCR1 (0.40) CCR1CCR8L3MBTL1ALDH1A1MAPT
SCHEMBL12577921 0.87 CYP11B1 (0.40) CCR1CCR8L3MBTL1PIK3CDMAPT
SCHEMBL12577915 0.87 CYP11B1 (0.41) CCR1CCR8L3MBTL1PIK3CDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10573823-B2 Organic electroluminescent device JOLED INC (JP) 2020-02-25 US disclosed
US-9978975-B2 Organic electroluminescence device JOLED INC (JP) 2018-05-22 US disclosed
US-9978975-B2 Organic electroluminescence device JOLED INC (JP) 2018-05-22 US disclosed
US-20160197289-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-07-07 US disclosed
US-20160197289-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2016-07-07 US disclosed
US-20150303380-A1 ORGANIC ELECTROLUMINESCENT DEVICE MAGNOLIA BLUE CORPORATION (JP) 2015-10-22 US disclosed
US-20150303380-A1 ORGANIC ELECTROLUMINESCENT DEVICE MAGNOLIA BLUE CORPORATION (JP) 2015-10-22 US disclosed
US-20150069351-A1 ORGANIC ELECTROLUMINESCENCE DEVICE MAGNOLIA BLUE CORPORATION (JP) 2015-03-12 US disclosed
EP-2833429-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT Sony Corporation (JP) 2015-02-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10573823-B2 Organic electroluminescent device L1CAM, NES, EML4 CCR1 2156/4885CCR8 2584/4885L3MBTL1 2054/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.