Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 3/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.57 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.57 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | KIFC1 | Q9BW19 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 3/20 | 0.35 |
| ▸ | CNR2 | P34972 | 3/20 | 0.35 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.35 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2229666 | 0.89 | HDAC4 (0.73) | HDAC4HDAC7HDAC8HDAC6HDAC9 | |
| SCHEMBL14752305 | 0.84 | HDAC4 (0.78) | HDAC4HDAC7HDAC8HDAC6HDAC9 | |
| SCHEMBL14752355 | 0.80 | HDAC4 (0.71) | HDAC4HDAC7HDAC8HDAC6HDAC9 | |
| SCHEMBL16435277 | 0.79 | HDAC8 (0.70) | HDAC4HDAC7HDAC8HDAC6HDAC9 | |
| SCHEMBL14752229 | 0.78 | HDAC4 (0.69) | HDAC4HDAC7HDAC8HDAC6HDAC9 | |
| SCHEMBL14752356 | 0.78 | HDAC4 (0.72) | HDAC4HDAC7HDAC8HDAC6HDAC9 | |
| SCHEMBL14752240 | 0.77 | HDAC4 (0.66) | HDAC4HDAC7HDAC8HDAC6HDAC9 | |
| SCHEMBL14752318 | 0.77 | HDAC4 (0.69) | HDAC4HDAC7HDAC8HDAC6HDAC9 | |
| SCHEMBL14752232 | 0.77 | HDAC4 (0.55) | HDAC4HDAC7HDAC8HDAC6HDAC9 | |
| SCHEMBL14752352 | 0.77 | HDAC4 (0.68) | HDAC4HDAC7HDAC8HDAC6HDAC9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150038534-A1 | COMPOUNDS AND METHODS | TEMPERO PHARMACEUTICALS, INC. | 2015-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150038534-A1 | COMPOUNDS AND METHODS | XDH, LPXN, CCNY | HDAC4 1441/4885HDAC7 1956/4885HDAC8 1583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.