Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.36 |
| ▸ | HTR1D | P28221 | 4/20 | 0.35 |
| ▸ | HTR1B | P28222 | 4/20 | 0.35 |
| ▸ | HTR2A | P28223 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6978166 | 0.90 | HDAC4 (0.48) | HDAC4HDAC6HDAC1HDAC7HDAC8 | |
| SCHEMBL16435288 | 0.90 | HDAC4 (0.43) | MCHR1HTR1DHTR1BHTR2AALDH1A1 | |
| SCHEMBL14752484 | 0.89 | KDR (0.37) | MCHR1SCN10AHDAC4HDAC6HDAC1 | |
| SCHEMBL16435290 | 0.86 | SCN10A (0.39) | ALDH1A1SCN10AMEN1TP53MAPT | |
| SCHEMBL14752528 | 0.86 | SCN10A (0.39) | ALDH1A1SCN10AMEN1MAPTKMT2A | |
| SCHEMBL14755003 | 0.86 | ABL1 (0.36) | MCHR1SCN10AHDAC4HDAC6HDAC1 | |
| SCHEMBL14752482 | 0.81 | MCHR1 (0.40) | MCHR1TP53CYP1A2HDAC4HDAC6 | |
| SCHEMBL6976800 | 0.80 | HDAC4 (0.56) | HDAC4HDAC6HDAC1HDAC7HDAC8 | |
| SCHEMBL14752421 | 0.78 | SCN10A (0.40) | SCN10ATP53MAPTHPGDKMT2A | |
| SCHEMBL14754961 | 0.78 | HDAC4 (0.42) | MCHR1HDAC4HDAC6HDAC1ULK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150038534-A1 | COMPOUNDS AND METHODS | TEMPERO PHARMACEUTICALS, INC. | 2015-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150038534-A1 | COMPOUNDS AND METHODS | XDH, LPXN, CCNY | MCHR1 2337/4885HTR1D 1973/4885HTR1B 990/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.