SCHEMBL16436610

SCHEMBL16436610

c1ccc(-c2cccc(-c3cc(-c4cccc(-c5ccccc5)c4)c4nc(-c5ccc(-c6ccncc6)cc5)nc(-c5ccc(-c6ccncc6)cc5)c4c3)c2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MKNK1 Q9BUB5 1/20 0.47
SMN1; SMN2 Q16637 4/20 0.44
PIK3CA P42336 1/20 0.43
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
MAPT P10636 2/20 0.40
NPC1 O15118 1/20 0.40
NFKB1 P19838 1/20 0.40
RAB9A P51151 1/20 0.40
NFKB2 Q00653 1/20 0.40
RELA Q04206 1/20 0.40
HSD17B10 Q99714 1/20 0.40
MAPK11 Q15759 3/20 0.39
MAPK14 Q16539 3/20 0.39
MAPK13 O15264 2/20 0.39
MAPK12 P53778 2/20 0.39
HPGD P15428 1/20 0.39
GCGR P47871 1/20 0.39
IMPDH2 P12268 1/20 0.39
ATM Q13315 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16436670 0.93 SMN1; SMN2 (0.48) MKNK1SMN1; SMN2PIK3CAMEN1KMT2A
SCHEMBL16436580 0.93 SMN1; SMN2 (0.48) MKNK1SMN1; SMN2PIK3CAMEN1KMT2A
SCHEMBL16436628 0.92 MEN1 (0.46) MKNK1PIK3CAMEN1KMT2AMAPT
SCHEMBL16436693 0.90 MKNK1 (0.41) MKNK1SMN1; SMN2PIK3CAMEN1KMT2A
SCHEMBL16436608 0.89 CYP11B1 (0.43) MKNK1SMN1; SMN2PIK3CAMEN1KMT2A
SCHEMBL16436536 0.89 MAPK9 (0.47) MKNK1SMN1; SMN2PIK3CAMAPK11MAPK14
SCHEMBL16436626 0.88 MEN1 (0.44) SMN1; SMN2MEN1KMT2AMAPTRAB9A
SCHEMBL16436627 0.88 MEN1 (0.44) SMN1; SMN2MEN1KMT2AMAPTRAB9A
SCHEMBL16436629 0.87 MEN1 (0.40) MEN1KMT2AMAPTRAB9AHPGD
SCHEMBL21664824 0.87 MEN1 (0.47) SMN1; SMN2MEN1KMT2AMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2842954-B1 COMPOUND FOR ORGANIC OPTOELECTRIC DEVICE, ORGANIC LIGHT EMITTING DEVICE CONTAINING SAME, AND DISPLAY DEVICE CONTAINING SAID ORGANIC LIGHT EMITTING DEVICE SAMSUNG SDI CO LTD (KR) 2020-02-05 EP disclosed
US-9324948-B2 Compound for organic optoelectronic device, organic light emitting diode including the same and display including the organic light emitting diode SAMSUNG SDI CO., LTD. (KR) 2016-04-26 US disclosed
US-9324948-B2 Compound for organic optoelectronic device, organic light emitting diode including the same and display including the organic light emitting diode SAMSUNG SDI CO., LTD. (KR) 2016-04-26 US disclosed
US-20150034938-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME AND DISPLAY INCLUDING THE ORGANIC LIGHT EMITTING DIODE SAMSUNG SDI CO., LTD. (KR) 2015-02-05 US disclosed
US-20150034938-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME AND DISPLAY INCLUDING THE ORGANIC LIGHT EMITTING DIODE SAMSUNG SDI CO., LTD. (KR) 2015-02-05 US disclosed