SCHEMBL16436670

SCHEMBL16436670

c1ccc(-c2cc(-c3ccccc3)c3nc(-c4ccc(-c5ccncc5)cc4)nc(-c4ccc(-c5ccncc5)cc4)c3c2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.48
MKNK1 Q9BUB5 1/20 0.47
PIK3CA P42336 1/20 0.46
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
MAPT P10636 3/20 0.42
NPC1 O15118 1/20 0.42
NFKB1 P19838 1/20 0.42
RAB9A P51151 1/20 0.42
NFKB2 Q00653 1/20 0.42
RELA Q04206 1/20 0.42
HSD17B10 Q99714 1/20 0.42
MAPK11 Q15759 2/20 0.42
MAPK14 Q16539 2/20 0.42
IMPDH2 P12268 1/20 0.42
CSNK1D P48730 1/20 0.42
NOTUM Q6P988 1/20 0.42
HPGD P15428 1/20 0.41
ATM Q13315 1/20 0.41
ALDH1A1 P00352 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16436580 1.00 SMN1; SMN2 (0.48) SMN1; SMN2MKNK1PIK3CAMEN1KMT2A
SCHEMBL16436610 0.93 MKNK1 (0.47) SMN1; SMN2MKNK1PIK3CAMEN1KMT2A
SCHEMBL16436682 0.91 MEN1 (0.49) MEN1KMT2AMAPTHSD17B10HPGD
SCHEMBL16436596 0.91 MEN1 (0.49) MEN1KMT2AMAPTHSD17B10HPGD
SCHEMBL16436576 0.88 CYP19A1 (0.46) SMN1; SMN2MKNK1PIK3CAMEN1KMT2A
SCHEMBL16436693 0.88 MKNK1 (0.41) SMN1; SMN2MKNK1PIK3CAMEN1KMT2A
SCHEMBL16436664 0.88 CYP19A1 (0.46) SMN1; SMN2MKNK1PIK3CAMEN1KMT2A
SCHEMBL16436597 0.87 MEN1 (0.47) SMN1; SMN2MEN1KMT2AMAPTHPGD
SCHEMBL16436681 0.87 MEN1 (0.47) SMN1; SMN2MEN1KMT2AMAPTHPGD
SCHEMBL16436598 0.87 MEN1 (0.47) SMN1; SMN2MEN1KMT2AMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2842954-B1 COMPOUND FOR ORGANIC OPTOELECTRIC DEVICE, ORGANIC LIGHT EMITTING DEVICE CONTAINING SAME, AND DISPLAY DEVICE CONTAINING SAID ORGANIC LIGHT EMITTING DEVICE SAMSUNG SDI CO LTD (KR) 2020-02-05 EP disclosed
US-9324948-B2 Compound for organic optoelectronic device, organic light emitting diode including the same and display including the organic light emitting diode SAMSUNG SDI CO., LTD. (KR) 2016-04-26 US disclosed
US-9324948-B2 Compound for organic optoelectronic device, organic light emitting diode including the same and display including the organic light emitting diode SAMSUNG SDI CO., LTD. (KR) 2016-04-26 US disclosed
US-20150034938-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME AND DISPLAY INCLUDING THE ORGANIC LIGHT EMITTING DIODE SAMSUNG SDI CO., LTD. (KR) 2015-02-05 US disclosed
US-20150034938-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME AND DISPLAY INCLUDING THE ORGANIC LIGHT EMITTING DIODE SAMSUNG SDI CO., LTD. (KR) 2015-02-05 US disclosed