SCHEMBL16437656

SCHEMBL16437656

c1ccc2c(c1)oc1ccc(-n3c4ccccc4c4c5oc6c(ccc7sc8ccccc8c76)c5ccc43)cc12

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.32
MAPT P10636 2/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32
RAB9A P51151 1/20 0.32
KMT2A Q03164 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16485009 0.95 MAPT (0.33) NPC1MAPTKDM4EMEN1ALDH1A1
SCHEMBL16483827 0.94 KDM4E (0.33) NPC1MAPTKDM4EMEN1ALDH1A1
SCHEMBL16484979 0.93 NPC1 (0.32) NPC1MAPTKDM4EMEN1ALDH1A1
SCHEMBL16437663 0.90 GPR3 (0.30) MAPTALDH1A1HPGDRAB9ASMN1; SMN2
SCHEMBL16437664 0.90 GPR3 (0.33) MAPTKDM4EMEN1ALDH1A1HPGD
SCHEMBL17246522 0.90 SMN1; SMN2 (0.35) NPC1MAPTKDM4EMEN1ALDH1A1
SCHEMBL16484957 0.90 NPC1 (0.30) NPC1MAPT
SCHEMBL16282993 0.89 ESR2 (0.33) MAPTMEN1ALDH1A1HPGDRAB9A
SCHEMBL16484590 0.89 MEN1 (0.40) NPC1MAPTKDM4EMEN1ALDH1A1
SCHEMBL16437653 0.88 KDM4E (0.33) NPC1MAPTKDM4EMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9755157-B2 Organic compound and organic optoelectric device and display device CHEIL INDUSTRIES, INC. (KR) 2017-09-05 US disclosed
US-9755157-B2 Organic compound and organic optoelectric device and display device CHEIL INDUSTRIES, INC. (KR) 2017-09-05 US disclosed
US-20150034914-A1 ORGANIC COMPOUND AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE CHEIL INDUSTRIES, INC. (KR) 2015-02-05 US disclosed
US-20150034914-A1 ORGANIC COMPOUND AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE CHEIL INDUSTRIES, INC. (KR) 2015-02-05 US disclosed