SCHEMBL16438643

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17796963	0.90	FABP4 (0.62)	FABP4CHRM3FABP5SERPINE1KDM4E
	SCHEMBL3970097	0.89	MEN1 (0.50)	FABP4CHRM3FABP3CHRM1DHODH
	SCHEMBL3910746	0.89	AKR1C4 (0.47)	FABP4CHRM3FABP5SERPINE1CHRM1
	SCHEMBL5100285	0.88	CHRM3 (0.56)	FABP4CHRM3CNR1CHRM1CHRM2
	SCHEMBL17796950	0.88	CHRM3 (0.52)	FABP4CHRM3FABP5SERPINE1CNR1
	SCHEMBL3913042	0.87	CHRM1 (0.56)	CHRM3KDM4ENPSR1CHRM1
	SCHEMBL17796921	0.87	FABP4 (0.48)	FABP4CHRM3FABP5SERPINE1KDM4E
	Hydrochloric Acid SCHEMBL5099086	0.86	CHRM1 (0.55)	CHRM3KDM4ENPSR1CHRM1
	SCHEMBL16438568	0.84	KMT2A (0.53)	FABP4CHRM3KDM4ENPSR1CNR1
	SCHEMBL10344931	0.84	PTGDR2 (0.58)	FABP4CHRM3FABP5SERPINE1CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.