Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CTSS | P25774 | 3/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | CTSB | P07858 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | TYR | P14679 | 2/20 | 0.35 |
| ▸ | NOS3 | P29474 | 2/20 | 0.35 |
| ▸ | NOS1 | P29475 | 2/20 | 0.35 |
| ▸ | NOS2 | P35228 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18870810 | 1.00 | ALDH1A1 (0.42) | ALDH1A1CTSSCTSKL3MBTL1CTSL | |
| SCHEMBL5988691 | 0.82 | ALDH1A1 (0.43) | ALDH1A1CTSSCTSKL3MBTL1CTSL | |
| SCHEMBL1806573 | 0.82 | ALDH1A1 (0.61) | ALDH1A1CTSSCTSKL3MBTL1TYR | |
| SCHEMBL15585678 | 0.82 | ALDH1A1 (0.61) | ALDH1A1CTSSCTSKL3MBTL1TYR | |
| SCHEMBL8234437 | 0.82 | ALDH1A1 (0.43) | ALDH1A1CTSSCTSKL3MBTL1CTSL | |
| SCHEMBL12018403 | 0.82 | ALDH1A1 (0.43) | ALDH1A1CTSSCTSKL3MBTL1CTSL | |
| SCHEMBL6469 | 0.82 | ALDH1A1 (0.61) | ALDH1A1CTSSCTSKL3MBTL1TYR | |
| SCHEMBL17772168 | 0.82 | ALDH1A1 (0.61) | ALDH1A1CTSSCTSKL3MBTL1TYR | |
| SCHEMBL204043 | 0.82 | ALDH1A1 (0.61) | ALDH1A1CTSSCTSKL3MBTL1TYR | |
| SCHEMBL3265293 | 0.82 | ALDH1A1 (0.43) | ALDH1A1CTSSCTSKL3MBTL1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015017382-A1 | HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2015-02-05 | — | — | WO | disclosed |