⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20856794 | 0.82 | FDPS (0.40) | — | |
| SCHEMBL10445899 | 0.79 | — | — | |
| SCHEMBL11986743 | 0.79 | — | — | |
| SCHEMBL28039816 | 0.72 | — | — | |
| SCHEMBL6037285 | 0.66 | TSHR (0.33) | — | |
| SCHEMBL20526098 | 0.65 | — | — | |
| SCHEMBL16497059 | 0.63 | — | — | |
| SCHEMBL28007570 | 0.62 | — | — | |
| SCHEMBL23643002 | 0.61 | — | — | |
| SCHEMBL21164857 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110097365-A1 | S-TRIAZINE DERIVATIVES CONTAINING AT LEAST TWO PARTICULAR SILANE AMINOBENZOATE OR SILANE AMINOBENZAMIDE GROUPS; PHOTOPROTECTIVE COSMETIC COMPOSITIONS CONTAINING THESE DERIVATIVES; USES OF THE SAID S-TRIAZINE DERIVATIVES | L'OREAL (FR) | 2011-04-28 | — | — | US | disclosed |
| EP-1535925-B1 | 4,4-Diarylbutadiene functionalized methyltrialkylsilanes and cosmetic or photoprotective dermatological compositions containing them | OREAL (FR) | 2009-05-27 | — | — | EP | disclosed |
| US-20090054369-A1 | PHARMACEUTICAL COMPOSITIONS OF SILICON-CONTAINING SUBSTITUTED ADENOSINE NUCLEOSIDE AMIDE ANALOGS | RND PHARMACEUTICALS, INC. (US) | 2009-02-26 | — | — | US | disclosed |
| US-7432386-B2 | Diarylbutadiene-substituted methyltrialkylsilanes and photoprotective compositions comprised thereof | L'OREAL (FR) | 2008-10-07 | — | — | US | disclosed |
| EP-1919929-A4 | PHARMACEUTICAL COMPOSITIONS OF SILICON-CONTAINING SUBSTITUTED ADENOSINE NUCLEOSIDE AMIDE ANALOGS | RND PHARMACEUTICALS INC (US) | 2008-08-06 | — | — | EP | disclosed |
| US-20080171802-A1 | Methyltrialkylsilanes containing a cinnamate, cinnamamide, benzalmalonamide or benzalmalonate function and photostabilizing methods | L'OREAL (FR) | 2008-07-17 | — | — | US | disclosed |
| EP-1919929-A2 | PHARMACEUTICAL COMPOSITIONS OF SILICON-CONTAINING SUBSTITUTED ADENOSINE NUCLEOSIDE AMIDE ANALOGS | RND Pharmaceuticals, Inc. (US) | 2008-05-14 | — | — | EP | disclosed |
| US-7354571-B2 | Photoprotective compositions comprising methyltrialkylsilanes containing a cinnamate, cinnamamide, benzalmalonamide or benzalmalonate function | L'OREAL (FR) | 2008-04-08 | — | — | US | disclosed |
| EP-1594880-B1 | PHOTOPROTECTIVE COMPOSITIONS BASED ON METHYLTRIALKYLSILANES CONTAINING A CINNAMATE, CINNAMAMIDE, BENZALMALONAMIDE OR BENZALMALONATE FUNCTION | OREAL (FR) | 2008-03-19 | — | — | EP | disclosed |
| US-20070213547-A1 | For UV-photoprotecting human skin against the damaging effects of UV-radiation, notably UV-A radiation; example: monotrimethylsilanylmethyl monoethyl diester of (3,3-diphenyl-2-propylidene)propanedioic acid; good resistance to water and to perspiration | L'OREAL | 2007-09-13 | — | — | US | disclosed |
| US-7229609-B2 | Diarylbutadiene-substituted methyltrialkylsilanes and photoprotective compositions comprised thereof | L'OREAL (FR) | 2007-06-12 | — | — | US | disclosed |
| WO-2007019221-A2 | PHARMACEUTICAL COMPOSITIONS OF SILICON-CONTAINING SUBSTITUTED ADENOSINE NUCLEOSIDE AMIDE ANALOGS | RND PHARMACEUTICALS, INC. (US) | 2007-02-15 | — | — | WO | disclosed |
| US-20060018848-A1 | Photoprotective compositions comprising methyltrialkylsilanes containing a cinnamate, cinnamamide, benzalmalonamide or benzalmalonate function | L'OREAL (FR) | 2006-01-26 | — | — | US | disclosed |
| US-20050201957-A1 | Diarylbutadiene-substituted methyltrialkylsilanes and photoprotective compositions comprised thereof | L'OREAL (FR) | 2005-09-15 | — | — | US | disclosed |
| EP-1535925-A1 | 4,4-Diarylbutadiene functionalized methyltrialkylsilanes and cosmetic or photoprotective dermatological compositions containing them | L'OREAL (FR) | 2005-06-01 | — | — | EP | disclosed |