Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 20/20 | 0.80 |
| ▸ | CYP3A4 | P08684 | 12/20 | 0.80 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.74 |
| ▸ | APLNR | P35414 | 1/20 | 0.74 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.74 |
| ▸ | GLP1R | P43220 | 1/20 | 0.74 |
| ▸ | CX3CR1 | P49238 | 1/20 | 0.74 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.74 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19549541 | 1.00 | GNRHR (0.80) | GNRHRCYP3A4ADRB2APLNROPRK1 | |
| SCHEMBL19549442 | 0.93 | GNRHR (0.91) | GNRHRCYP3A4ADRB2APLNROPRK1 | |
| SCHEMBL29722073 | 0.93 | GNRHR (0.91) | GNRHRCYP3A4ADRB2APLNROPRK1 | |
| SCHEMBL1642456 | 0.93 | GNRHR (0.91) | GNRHRCYP3A4ADRB2APLNROPRK1 | |
| SCHEMBL5762499 | 0.93 | GNRHR (0.91) | GNRHRCYP3A4ADRB2APLNROPRK1 | |
| SCHEMBL5002181 | 0.93 | GNRHR (0.87) | GNRHRCYP3A4ADRB2APLNROPRK1 | |
| SCHEMBL1643488 | 0.93 | GNRHR (0.87) | GNRHRCYP3A4ADRB2APLNROPRK1 | |
| Hydrochloric Acid SCHEMBL1643496 | 0.93 | GNRHR (0.90) | GNRHRCYP3A4ADRB2APLNROPRK1 | |
| Hydrochloric Acid SCHEMBL29960614 | 0.93 | GNRHR (0.90) | GNRHRCYP3A4ADRB2APLNROPRK1 | |
| SCHEMBL1643218 | 0.93 | GNRHR (0.86) | GNRHRCYP3A4ADRB2APLNROPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11459305-B2 | Processes for the preparation of uracil derivatives | NEUROCRINE BIOSCIENCES, INC. (US) | 2022-10-04 | — | — | US | disclosed |
| US-20200255387-A1 | PROCESSES FOR THE PREPARATION OF URACIL DERIVATIVES | NEUROCRINE BIOSCIENCES, INC. | 2020-08-13 | — | — | US | disclosed |
| US-20200255387-A1 | PROCESSES FOR THE PREPARATION OF URACIL DERIVATIVES | NEUROCRINE BIOSCIENCES, INC. | 2020-08-13 | — | — | US | disclosed |
| US-20190218191-A1 | PROCESSES FOR THE PREPARATION OF URACIL DERIVATIVES | NEUROCRINE BIOSCIENCES, INC. | 2019-07-18 | — | — | US | disclosed |
| US-20190218191-A1 | PROCESSES FOR THE PREPARATION OF URACIL DERIVATIVES | NEUROCRINE BIOSCIENCES, INC. | 2019-07-18 | — | — | US | disclosed |
| US-20180346428-A1 | PROCESSES FOR THE PREPARATION OF URACIL DERIVATIVES | NEUROCRINE BIOSCIENCES, INC. | 2018-12-06 | — | — | US | disclosed |
| US-9868706-B2 | Processes for the preparation of uracil derivatives | NEUROCRINE BIOSCIENCES, INC. (US) | 2018-01-16 | — | — | US | disclosed |
| US-20170320836-A1 | PROCESSES FOR THE PREPARATION OF URACIL DERIVATIVES | NEUROCRINE BIOSCIENCES, INC. | 2017-11-09 | — | — | US | disclosed |
| US-20170320836-A1 | PROCESSES FOR THE PREPARATION OF URACIL DERIVATIVES | NEUROCRINE BIOSCIENCES, INC. | 2017-11-09 | — | — | US | disclosed |
| US-9382214-B2 | Processes for the preparation of uracil derivatives | Neurocine Biosciences, Inc. (US) | 2016-07-05 | — | — | US | disclosed |
| US-9382214-B2 | Processes for the preparation of uracil derivatives | Neurocine Biosciences, Inc. (US) | 2016-07-05 | — | — | US | disclosed |
| US-8765948-B2 | Processes for the preparation of uracil derivatives | NEUROCRINE BIOSCIENCES, INC. (US) | 2014-07-01 | — | — | US | disclosed |
| US-8765948-B2 | Processes for the preparation of uracil derivatives | NEUROCRINE BIOSCIENCES, INC. (US) | 2014-07-01 | — | — | US | disclosed |
| US-20110098472-A1 | PROCESSES FOR THE PREPARATION OF URACIL DERIVATIVES | NEUROCRINE BIOSCIENCES, INC. | 2011-04-28 | — | — | US | disclosed |
| US-20110098472-A1 | PROCESSES FOR THE PREPARATION OF URACIL DERIVATIVES | NEUROCRINE BIOSCIENCES, INC. | 2011-04-28 | — | — | US | disclosed |
| WO-2009062087-A1 | PROCESSES FOR THE PREPARATION OF URACIL DERIVATIVES | NEUROCRINE BIOSCIENCES, INC. (US) | 2009-05-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200255387-A1 | PROCESSES FOR THE PREPARATION OF URACIL DERIVATIVES | GNRHR, FSHR, GHRHR | GNRHR 1/4885CYP3A4 1033/4885ADRB2 1892/4885 |
| US-20190218191-A1 | PROCESSES FOR THE PREPARATION OF URACIL DERIVATIVES | GNRHR, FSHR, GHRHR | GNRHR 1/4885CYP3A4 1033/4885ADRB2 1892/4885 |
| US-20180346428-A1 | PROCESSES FOR THE PREPARATION OF URACIL DERIVATIVES | GNRHR, FSHR, GHRHR | GNRHR 1/4885CYP3A4 1033/4885ADRB2 1892/4885 |
| US-20110098472-A1 | PROCESSES FOR THE PREPARATION OF URACIL DERIVATIVES | GNRHR, FSHR, GHRHR | GNRHR 1/4885CYP3A4 1033/4885ADRB2 1892/4885 |
| US-20170320836-A1 | PROCESSES FOR THE PREPARATION OF URACIL DERIVATIVES | GNRHR, FSHR, GHRHR | GNRHR 1/4885CYP3A4 1033/4885ADRB2 1892/4885 |
| US-11459305-B2 | Processes for the preparation of uracil derivatives | GNRHR, FSHR, GHRHR | GNRHR 1/4885CYP3A4 1033/4885ADRB2 1892/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.