Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 4/20 | 0.41 |
| ▸ | ENPP1 | P22413 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | PTPN7 | P35236 | 3/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.38 |
| ▸ | PTP4A1 | Q93096 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23504077 | 0.77 | HSD17B10 (0.59) | HSD17B10KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL16441961 | 0.77 | HSD17B10 (0.46) | HSD17B10KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL16432305 | 0.77 | SMN1; SMN2 (0.48) | HSD17B10KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL23504048 | 0.77 | HSD17B10 (0.55) | HSD17B10KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL16441964 | 0.76 | KDM4E (0.45) | HSD17B10KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL16441960 | 0.75 | KDM4E (0.44) | HSD17B10KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL18083389 | 0.74 | HSD17B10 (0.62) | HSD17B10KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL23504047 | 0.70 | HSD17B10 (0.67) | HSD17B10KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL30282194 | 0.70 | SMN1; SMN2 (0.66) | HSD17B10KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL16432493 | 0.70 | SMN1; SMN2 (0.66) | HSD17B10KDM4ESMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015014791-A1 | BENZIMIDAZOLO[2,1-B][1,3]BENZOTHIAZOLES FOR ELECTRONIC APPLICATIONS | BASF SE (DE) | 2015-02-05 | — | — | WO | disclosed |