Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 9/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16441961 | 0.82 | HSD17B10 (0.46) | KDM4EHSD17B10TP53MAPTGRIN2B | |
| SCHEMBL16441913 | 0.81 | TP53 (0.44) | KDM4EHSD17B10TP53MAPTRXFP1 | |
| SCHEMBL16441960 | 0.80 | KDM4E (0.44) | KDM4EHSD17B10TP53MAPTNPC1 | |
| SCHEMBL16441920 | 0.76 | HSD17B10 (0.52) | KDM4EHSD17B10TP53MAPTNPC1 | |
| SCHEMBL16441938 | 0.73 | SMN1; SMN2 (0.43) | KDM4EHSD17B10TP53MAPTNPC1 | |
| SCHEMBL16441947 | 0.71 | SMN1; SMN2 (0.47) | KDM4EHSD17B10TP53MAPTNPC1 | |
| SCHEMBL20929361 | 0.71 | HSD17B10 (0.49) | KDM4EHSD17B10TP53MAPTNPC1 | |
| SCHEMBL23504077 | 0.70 | HSD17B10 (0.59) | KDM4EHSD17B10TP53MAPTNPC1 | |
| SCHEMBL16441934 | 0.70 | HSD17B10 (0.43) | KDM4EHSD17B10TP53MAPTNPC1 | |
| SCHEMBL16441887 | 0.70 | RAB9A (0.55) | KDM4EHSD17B10TP53MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015014791-A1 | BENZIMIDAZOLO[2,1-B][1,3]BENZOTHIAZOLES FOR ELECTRONIC APPLICATIONS | BASF SE (DE) | 2015-02-05 | — | — | WO | disclosed |