Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | GRK6 | P43250 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16424488 | 0.86 | AVPR1B (0.47) | — | |
| SCHEMBL16442162 | 0.76 | HRH3 (0.45) | — | |
| SCHEMBL16423577 | 0.71 | AVPR1B (0.49) | RXFP1 | |
| SCHEMBL1687403 | 0.71 | AVPR1B (0.53) | — | |
| SCHEMBL1687126 | 0.71 | NR1I2 (0.41) | BACE1NR1I2SMN1; SMN2RXFP1 | |
| SCHEMBL16423724 | 0.70 | AVPR1B (0.45) | TP53 | |
| SCHEMBL16424422 | 0.70 | AVPR1B (0.48) | RXFP1 | |
| SCHEMBL11689268 | 0.70 | ABCB1 (0.50) | BACE1ERN1ESR1ESR2 | |
| SCHEMBL16424185 | 0.68 | AVPR1B (0.57) | — | |
| SCHEMBL15354 | 0.67 | MAOB (0.61) | BACE1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2832722-A1 | FUSED AZOLE DERIVATIVE | Taisho Pharmaceutical Co., Ltd. (JP) | 2015-02-04 | — | — | EP | disclosed |