Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.45 |
| ▸ | HRH2 | P25021 | 3/20 | 0.45 |
| ▸ | HRH1 | P35367 | 3/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16424320 | 0.89 | AVPR1B (0.49) | HRH3 | |
| SCHEMBL16423585 | 0.85 | AVPR1B (0.47) | HRH3HRH2HRH1 | |
| SCHEMBL16445077 | 0.81 | AVPR1B (0.48) | HRH3HRH2HRH1 | |
| SCHEMBL16423839 | 0.81 | AVPR1B (0.57) | — | |
| SCHEMBL16424040 | 0.76 | AVPR1B (0.55) | HRH3KCNH2 | |
| SCHEMBL16442153 | 0.76 | BACE1 (0.39) | — | |
| SCHEMBL16423675 | 0.75 | AVPR1B (0.59) | — | |
| SCHEMBL16423778 | 0.74 | AVPR1B (0.47) | — | |
| SCHEMBL16423724 | 0.73 | AVPR1B (0.45) | — | |
| SCHEMBL6857474 | 0.72 | AVPR1B (0.45) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2832722-A1 | FUSED AZOLE DERIVATIVE | Taisho Pharmaceutical Co., Ltd. (JP) | 2015-02-04 | — | — | EP | disclosed |