Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10188227 | 0.92 | GAA (0.37) | DPP4 | |
| SCHEMBL25105760 | 0.80 | KAT2B (0.32) | NCF1 | |
| SCHEMBL25105768 | 0.80 | KAT2B (0.32) | NCF1 | |
| SCHEMBL25106077 | 0.80 | KAT2B (0.32) | NCF1 | |
| SCHEMBL25106078 | 0.80 | KAT2B (0.32) | NCF1 | |
| SCHEMBL25105758 | 0.80 | KAT2B (0.32) | NCF1 | |
| SCHEMBL13576372 | 0.79 | NCF1 (0.32) | NCF1 | |
| SCHEMBL13713091 | 0.79 | NCF1 (0.32) | NCF1 | |
| SCHEMBL14292565 | 0.78 | — | — | |
| SCHEMBL735810 | 0.77 | SMN1; SMN2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8946422-B2 | 8-methoxy-9H-isothiazolo[5,4-B]quinoline-3,4-diones and related compounds as anti-infective agents | ACHILLION PHARMACEUTICALS, INC. (US) | 2015-02-03 | — | — | US | disclosed |