Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 20/20 | 1.00 |
| ▸ | TNKS2 | Q9H2K2 | 6/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15289104 | 1.00 | TNKS (1.00) | TNKSTNKS2CYP3A4PARP2 | |
| SCHEMBL16444847 | 1.00 | TNKS (1.00) | TNKSTNKS2CYP3A4PARP2 | |
| SCHEMBL16444466 | 0.86 | TNKS (0.75) | TNKSTNKS2 | |
| SCHEMBL15289103 | 0.86 | TNKS (0.75) | TNKSTNKS2 | |
| SCHEMBL16444468 | 0.86 | TNKS (0.75) | TNKSTNKS2 | |
| SCHEMBL16456393 | 0.77 | TNKS (0.61) | TNKS | |
| SCHEMBL15289065 | 0.76 | TNKS (1.00) | TNKSTNKS2CYP3A4PARP2 | |
| SCHEMBL16444005 | 0.76 | TNKS (1.00) | TNKSTNKS2CYP3A4PARP2 | |
| SCHEMBL16444006 | 0.76 | TNKS (1.00) | TNKSTNKS2CYP3A4PARP2 | |
| SCHEMBL15289217 | 0.74 | TNKS (1.00) | TNKSTNKS2CYP3A4PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9340549-B2 | Oxazolidinone compounds and derivatives thereof | AMGEN INC. (US) | 2016-05-17 | — | — | US | disclosed |
| US-20150045368-A1 | OXAZOLIDINONE COMPOUNDS AND DERIVATIVES THEREOF | AMGEN INC. | 2015-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150045368-A1 | OXAZOLIDINONE COMPOUNDS AND DERIVATIVES THEREOF | TNKS1BP1, TNKS, TBKBP1 | TNKS 2/4885TNKS2 10/4885CYP3A4 741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.