SCHEMBL1644494

SCHEMBL1644494

NC1CCN(CC(=O)O)CC1

nearest known ligand 0.61

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.48
ITGB3 P05106 2/20 0.40
ITGA2B P08514 2/20 0.40
ALOX15 P16050 1/20 0.39
GNAI3 P08754 2/20 0.38
GNAO1 P09471 2/20 0.38
GNAI1 P63096 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.36
ACE P12821 1/20 0.35
SLC6A9 P48067 1/20 0.35
KDM4E B2RXH2 1/20 0.34
SMYD3 Q9H7B4 1/20 0.34
CACNA1B Q00975 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL188132 1.00 HSD17B10 (0.48) HSD17B10ITGB3ITGA2BALOX15GNAI3
Hydrochloric Acid SCHEMBL25226809 0.98 HSD17B10 (0.47) HSD17B10ITGB3ITGA2BALOX15GNAI3
SCHEMBL2362299 0.87 HSD17B10 (0.41) HSD17B10ITGB3ITGA2BALOX15GNAI3
SCHEMBL29954077 0.87 HSD17B10 (0.41) HSD17B10ITGB3ITGA2BALOX15GNAI3
SCHEMBL2362301 0.87 HSD17B10 (0.41) HSD17B10ITGB3ITGA2BALOX15GNAI3
SCHEMBL29392309 0.84 GNAI3 (0.39) GNAI3GNAO1GNAI1SMN1; SMN2KDM4E
SCHEMBL23291292 0.84 HSD17B10 (0.56) HSD17B10ITGB3ITGA2BALOX15ACE
SCHEMBL1007625 0.82 KDM4E (0.54) GNAI3GNAO1GNAI1SMN1; SMN2KDM4E
SCHEMBL18872667 0.81 HSD17B10 (0.40) HSD17B10SMN1; SMN2
SCHEMBL2718426 0.80 GNAI3 (0.41) GNAI3GNAO1GNAI1SMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024063648-A1 Platform and scaffold for FAP targeting agents ERASMUS UNIVERSITY MEDICAL CENTER ROTTERDAM (NL) 2024-03-28 WO claimed
EP-4342890-A1 PLATFORM AND SCAFFOLD FOR FAP TARGETING AGENTS Erasmus University Rotterdam Medical Center (NL) 2024-03-27 EP claimed
EP-4342890-A1 PLATFORM AND SCAFFOLD FOR FAP TARGETING AGENTS Erasmus University Rotterdam Medical Center (NL) 2024-03-27 EP disclosed
WO-2023229458-A1 RADIOISOTOPE LABELED SSTR2-AGONISTS WITH LINKERS ERASMUS UNIVERSITY MEDICAL CENTER ROTTERDAM (NL) 2023-11-30 WO disclosed
EP-4282439-A1 RADIOISOTOPE LABELED SSTR2-AGONISTS WITH LINKERS Erasmus University Rotterdam Medical Center (NL) 2023-11-29 EP disclosed
EP-2252628-B1 BOMBESIN ANALOG PEPTIDE ANTAGONIST CONJUGATES UNIVERSITÄTSSPITAL BASEL (CH) 2016-12-28 EP disclosed
US-9035023-B2 Bombesin analog peptide antagonist conjugates Piramal Imaging, SA (CH) 2015-05-19 US disclosed
US-20110097266-A1 Bombesin Analog Peptide Antagonist Conjugates BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2011-04-28 US disclosed
EP-2100900-A1 Bombesin analog peptide antagonist conjugates Universitätsspital Basel (CH) 2009-09-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110097266-A1 Bombesin Analog Peptide Antagonist Conjugates BRS3, VIP, GRPR HSD17B10 4724/4885ITGB3 2566/4885ITGA2B 1764/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.