SCHEMBL16446249

SCHEMBL16446249

CC(C[Si]1(C)CCCC(C)(C)O1)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 5/20 0.35
AOC3 Q16853 2/20 0.33
TRPA1 O75762 3/20 0.32
RIPK1 Q13546 1/20 0.32
CYP3A4 P08684 1/20 0.31
HPGD P15428 1/20 0.31
CYP2C19 P33261 1/20 0.31
RAB9A P51151 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
GFER P55789 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2404033 0.75 TAAR1 (0.39) TAAR1AOC3TRPA1RIPK1CYP3A4
SCHEMBL15270498 0.69
SCHEMBL3263249 0.67
SCHEMBL10713266 0.66 TAAR1 (0.48) TAAR1AOC3TRPA1RIPK1KDM4E
SCHEMBL182249 0.65
SCHEMBL17721898 0.64
Ammonia Solution, Strong SCHEMBL7586755 0.64
SCHEMBL28912813 0.64
SCHEMBL7771377 0.64 TAAR1 (0.39) TAAR1AOC3TRPA1RIPK1CYP3A4
SCHEMBL10903008 0.63 HPGD (0.36) TAAR1AOC3TRPA1RIPK1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180147133-A1 COSMETIC COMPOSITIONS CONTAINING SILICONES DOW CORNING EUROPE SA (BE) 2018-05-31 US disclosed
US-9913795-B2 Cosmetic compositions containing silicones DOW CORNING CORPORATION (US) 2018-03-13 US disclosed
US-20160184214-A1 COSMETIC COMPOSITIONS CONTAINING SILICONES DOW CORNING CORPORATION (US) 2016-06-30 US disclosed
EP-3030215-A1 COSMETIC COMPOSITIONS COMPRISING ORGANOPOLYSILICONES Dow Corning Corporation (US) 2016-06-15 EP disclosed
WO-2015018853-A1 COSMETIC COMPOSITIONS COMPRISING ORGANOPOLYSILICONES DOW CORNING CORPORATION (US) 2015-02-12 WO disclosed