Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.72 |
| ▸ | SYK | P43405 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | FOS | P01100 | 1/20 | 0.54 |
| ▸ | JUN | P05412 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | SIRT5 | Q9NXA8 | 7/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11584083 | 0.93 | ALDH1A1 (0.75) | ALDH1A1SYKMAPTSMN1; SMN2LMNA | |
| SCHEMBL28456194 | 0.88 | ALDH1A1 (0.75) | ALDH1A1SYKMAPTSMN1; SMN2LMNA | |
| SCHEMBL2019145 | 0.87 | ALDH1A1 (0.80) | ALDH1A1SYKMAPTSMN1; SMN2LMNA | |
| SCHEMBL29508864 | 0.86 | ALDH1A1 (0.76) | ALDH1A1SYKMAPTSMN1; SMN2LMNA | |
| SCHEMBL28734926 | 0.86 | ALDH1A1 (0.76) | ALDH1A1SYKMAPTSMN1; SMN2LMNA | |
| SCHEMBL1521580 | 0.84 | ALDH1A1 (0.76) | ALDH1A1SYKMAPTSMN1; SMN2LMNA | |
| SCHEMBL11157944 | 0.84 | ALDH1A1 (1.00) | ALDH1A1SYKMAPTSMN1; SMN2LMNA | |
| SCHEMBL1521842 | 0.80 | ALDH1A1 (0.70) | ALDH1A1SYKMAPTSMN1; SMN2LMNA | |
| SCHEMBL29545771 | 0.80 | ALDH1A1 (0.70) | ALDH1A1SYKMAPTSMN1; SMN2LMNA | |
| SCHEMBL23141936 | 0.80 | ALDH1A1 (0.69) | ALDH1A1SYKMAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015019037-A1 | PHARMACEUTICAL COMPOUNDS | ALMAC DISCOVERY LIMITED (GB) | 2015-02-12 | — | — | WO | disclosed |