Sugi Predict

Sugi Predict / Compounds / Chlorfenapyr

Chlorfenapyr

Chlorfenapyr

SCHEMBL16446552

CC(O)(c1ccc(Cl)cc1)c1ccc(Cl)cc1.CCOCn1c(-c2ccc(Cl)cc2)c(C#N)c(Br)c1C(F)(F)F

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 2/20 0.35
▸ KMT2A Q03164 2/20 0.35
▸ RXFP1 Q9HBX9 1/20 0.33
▸ GRIA2 P42262 1/20 0.31
▸ GRIA4 P48058 1/20 0.31
▸ KDM4E B2RXH2 1/20 0.31
▸ ALDH1A1 P00352 1/20 0.31
▸ HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chlorfenapyr SCHEMBL28508419 0.92 RXFP1 (0.36) MEN1KMT2ARXFP1GRIA2GRIA4
Chlorfenapyr SCHEMBL40337 0.92 RXFP1 (0.35) MEN1KMT2ARXFP1GRIA2GRIA4
Chlorfenapyr SCHEMBL27488880 0.91 RXFP1 (0.35) MEN1KMT2ARXFP1GRIA2GRIA4
Chlorfenapyr SCHEMBL28530561 0.91 RXFP1 (0.35) MEN1KMT2ARXFP1GRIA2GRIA4
SCHEMBL5813013 0.87 KIF11 (0.35) RXFP1ALDH1A1
Chlorfenapyr SCHEMBL28649822 0.86 GRIA2 (0.37) MEN1KMT2ARXFP1GRIA2GRIA4
Chlorfenapyr SCHEMBL28402415 0.85 RXFP1 (0.32) RXFP1GRIA2GRIA4KDM4EALDH1A1
SCHEMBL9567374 0.84 RXFP1 (0.34) MEN1KMT2ARXFP1GRIA2GRIA4
SCHEMBL9389300 0.84 — —
SCHEMBL9389580 0.84 AR (0.39) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015018870-A1 AGROCHEMICAL FORMULATIONS WITH IMPROVED DRIFT CONTROL LAMBERTI SPA (IT) 2015-02-12 — — WO disclosed