Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 4/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | UNG | P13051 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17996918 | 0.99 | TTR (0.39) | TTRALBPLAUPLA2G2AALDH1A1 | |
| SCHEMBL16450538 | 0.88 | MAOB (0.42) | TTRALBMAOB | |
| SCHEMBL16491041 | 0.88 | PLA2G2A (0.37) | TTRALBPLAUPLA2G2AALDH1A1 | |
| SCHEMBL22536864 | 0.86 | TTR (0.41) | TTRALBMAOBPOLB | |
| SCHEMBL16446801 | 0.85 | PLAU (0.37) | TTRALBPLAUMAOBPOLB | |
| SCHEMBL20097655 | 0.82 | CYSLTR2 (0.34) | ALDH1A1MAOB | |
| SCHEMBL16447138 | 0.82 | CYSLTR2 (0.34) | ALDH1A1MAOB | |
| SCHEMBL17996549 | 0.82 | HTR2A (0.36) | ALDH1A1HPGDMAOB | |
| SCHEMBL18018673 | 0.81 | CYSLTR2 (0.34) | ALDH1A1MAOB | |
| SCHEMBL16447428 | 0.80 | PLA2G2A (0.40) | PLAUPLA2G2AALDH1A1HPGDMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12060383-B2 | Protected fluorescent reagent compounds | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2024-08-13 | — | — | US | disclosed |
| US-12037641-B2 | Modified nucleotide reagents | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2024-07-16 | — | — | US | disclosed |
| US-12037641-B2 | Modified nucleotide reagents | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2024-07-16 | — | — | US | disclosed |
| US-20230192749-A1 | PROTECTED FLUORESCENT REAGENT COMPOUNDS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2023-06-22 | — | — | US | disclosed |
| US-20230192749-A1 | PROTECTED FLUORESCENT REAGENT COMPOUNDS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2023-06-22 | — | — | US | disclosed |
| US-11578093-B2 | Protected fluorescent reagent compounds | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2023-02-14 | — | — | US | disclosed |
| US-11578093-B2 | Protected fluorescent reagent compounds | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2023-02-14 | — | — | US | disclosed |
| US-20220396702-A1 | PROTECTED DYE-LABELED REAGENTS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2022-12-15 | — | — | US | disclosed |
| US-11466319-B2 | Labeled nucleotide analogs, reaction mixtures, and methods and systems for sequencing | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2022-10-11 | — | — | US | disclosed |
| US-11359235-B2 | Modified nucleotide reagents | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2022-06-14 | — | — | US | disclosed |
| US-20160237279-A1 | MULTIMERIC PROTECTED FLUORESCENT REAGENTS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2016-08-18 | — | — | US | disclosed |
| US-20160237279-A1 | MULTIMERIC PROTECTED FLUORESCENT REAGENTS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2016-08-18 | — | — | US | disclosed |
| WO-2016126941-A1 | MULTIMERIC PROTECTED FLUORESCENT REAGENTS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2016-08-11 | — | — | WO | disclosed |
| WO-2016126941-A1 | MULTIMERIC PROTECTED FLUORESCENT REAGENTS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2016-08-11 | — | — | WO | disclosed |
| EP-3030683-A1 | PROTECTED FLUORESCENT REAGENT COMPOUNDS | Pacific Biosciences Of California, Inc. (US) | 2016-06-15 | — | — | EP | disclosed |
| US-20150050659-A1 | PROTECTED FLUORESCENT REAGENT COMPOUNDS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2015-02-19 | — | — | US | disclosed |
| US-20150050659-A1 | PROTECTED FLUORESCENT REAGENT COMPOUNDS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2015-02-19 | — | — | US | disclosed |
| US-20150050659-A1 | PROTECTED FLUORESCENT REAGENT COMPOUNDS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2015-02-19 | — | — | US | disclosed |
| WO-2015021079-A1 | PROTECTED FLUORESCENT REAGENT COMPOUNDS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2015-02-12 | — | — | WO | disclosed |
| WO-2015021079-A1 | PROTECTED FLUORESCENT REAGENT COMPOUNDS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2015-02-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11359235-B2 | Modified nucleotide reagents | POLL, POLN, POLM | TTR 402/4885ALB 806/4885PLAU 3925/4885 |
| US-20150050659-A1 | PROTECTED FLUORESCENT REAGENT COMPOUNDS | ERCC4, ERCC2, ERCC1 | TTR 642/4885ALB 1400/4885PLAU 2643/4885 |
| US-12037641-B2 | Modified nucleotide reagents | POLL, POLN, POLM | TTR 402/4885ALB 806/4885PLAU 3925/4885 |
| US-20220396702-A1 | PROTECTED DYE-LABELED REAGENTS | POLL, POLB, POLM | TTR 349/4885ALB 642/4885PLAU 3852/4885 |
| US-11578093-B2 | Protected fluorescent reagent compounds | ERCC4, ERCC2, ERCC1 | TTR 642/4885ALB 1400/4885PLAU 2643/4885 |
| US-12060383-B2 | Protected fluorescent reagent compounds | ERCC4, ERCC2, ERCC1 | TTR 642/4885ALB 1400/4885PLAU 2643/4885 |
| US-20230192749-A1 | PROTECTED FLUORESCENT REAGENT COMPOUNDS | ERCC4, ERCC2, ERCC1 | TTR 642/4885ALB 1400/4885PLAU 2643/4885 |
| US-11466319-B2 | Labeled nucleotide analogs, reaction mixtures, and methods and systems for sequencing | POLL, POLN, POLB | TTR 538/4885ALB 969/4885PLAU 4087/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.