Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCNN1A | P37088 | 10/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL16446588 | 0.84 | ALDH1A1 (0.42) | SCNN1AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL16447291 | 0.83 | SCNN1A (0.41) | SCNN1A | |
| Hydrochloric Acid SCHEMBL16446565 | 0.79 | MEN1 (0.43) | SCNN1AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL20683803 | 0.71 | SCNN1A (0.54) | SCNN1ADRD2 | |
| SCHEMBL16443462 | 0.69 | SCNN1A (0.49) | SCNN1A | |
| SCHEMBL16453260 | 0.68 | SCNN1A (0.58) | SCNN1A | |
| Hydrochloric Acid SCHEMBL20677525 | 0.67 | SCNN1A (0.57) | SCNN1A | |
| SCHEMBL16443690 | 0.67 | SCNN1A (0.54) | SCNN1A | |
| Hydrochloric Acid SCHEMBL16446857 | 0.66 | POLB (0.43) | SCNN1AALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL16447320 | 0.66 | SCNN1A (0.40) | SCNN1AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3030555-A1 | NOVEL PYRAZINE AMIDE COMPOUNDS | Boehringer Ingelheim International GmbH (DE) | 2016-06-15 | — | — | EP | disclosed |
| WO-2015018754-A1 | NOVEL PYRAZINE AMIDE COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-02-12 | — | — | WO | disclosed |