Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 3/20 | 0.56 |
| ▸ | SCNN1A | P37088 | 6/20 | 0.53 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.43 |
| ▸ | PDE2A | O00408 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16455832 | 0.76 | SCNN1A (0.56) | CTSASCNN1A | |
| Hydrochloric Acid SCHEMBL16443497 | 0.75 | SCNN1A (0.55) | CTSASCNN1A | |
| Hydrochloric Acid SCHEMBL16446844 | 0.73 | UTS2R (0.42) | CTSASCNN1AUTS2R | |
| SCHEMBL12804187 | 0.72 | CTSA (1.00) | CTSASCNN1A | |
| SCHEMBL20683833 | 0.72 | SCNN1A (0.51) | CTSASCNN1ATAS1R3TAS1R1 | |
| SCHEMBL16453262 | 0.71 | SCNN1A (0.58) | SCNN1A | |
| SCHEMBL20683754 | 0.71 | SCNN1A (0.58) | SCNN1A | |
| Hydrochloric Acid SCHEMBL20677538 | 0.70 | SCNN1A (0.57) | SCNN1A | |
| Hydrochloric Acid SCHEMBL20677537 | 0.70 | SCNN1A (0.57) | SCNN1A | |
| SCHEMBL11959318 | 0.70 | SCNN1A (0.61) | SCNN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3030555-A1 | NOVEL PYRAZINE AMIDE COMPOUNDS | Boehringer Ingelheim International GmbH (DE) | 2016-06-15 | — | — | EP | disclosed |
| WO-2015018754-A1 | NOVEL PYRAZINE AMIDE COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-02-12 | — | — | WO | disclosed |