Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCNN1A | P37088 | 11/20 | 0.51 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.45 |
| ▸ | CTSA | P10619 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2074093 | 0.77 | SCNN1A (0.56) | SCNN1A | |
| SCHEMBL16453280 | 0.76 | SCNN1A (0.55) | SCNN1A | |
| Hydrochloric Acid SCHEMBL1134530 | 0.76 | SCNN1A (0.55) | SCNN1A | |
| Hydrochloric Acid SCHEMBL1134670 | 0.76 | SCNN1A (0.55) | SCNN1A | |
| SCHEMBL16453144 | 0.76 | SCNN1A (0.55) | SCNN1ACTSA | |
| SCHEMBL20683744 | 0.75 | SCNN1A (0.42) | SCNN1A | |
| SCHEMBL12779712 | 0.75 | SCNN1A (0.52) | SCNN1A | |
| SCHEMBL20683828 | 0.75 | KCNH2 (0.50) | SCNN1ACTSA | |
| SCHEMBL1134593 | 0.75 | SCNN1A (0.70) | SCNN1A | |
| SCHEMBL12087448 | 0.74 | SCNN1A (0.47) | SCNN1ATAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3030555-B1 | NOVEL PYRAZINE AMIDE COMPOUNDS | BOEHRINGER INGELHEIM INT (DE) | 2019-01-30 | — | — | EP | disclosed |