SCHEMBL16447665

SCHEMBL16447665

O=C(NC(=O)c1c(F)cccc1F)Nc1ccc(OC(F)(F)C(F)OCCOC(F)(F)F)c(Cl)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 8/20 0.55
KMT2A Q03164 8/20 0.55
MAPT P10636 8/20 0.55
USP2 O75604 1/20 0.55
ALOX15 P16050 1/20 0.55
NPC1 O15118 7/20 0.40
RAB9A P51151 7/20 0.40
SMN1; SMN2 Q16637 6/20 0.40
PKM P14618 1/20 0.39
TDP1 Q9NUW8 3/20 0.39
HTT P42858 3/20 0.39
POLB P06746 2/20 0.39
NPSR1 Q6W5P4 2/20 0.39
NFKB1 P19838 1/20 0.39
NFKB2 Q00653 1/20 0.39
RELA Q04206 1/20 0.39
KDM4E B2RXH2 2/20 0.39
GAA P10253 2/20 0.39
THRB P10828 1/20 0.39
RECQL P46063 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Novaluron SCHEMBL26984 0.88 MEN1 (0.60) MEN1KMT2AMAPTUSP2ALOX15
Novaluron SCHEMBL4137715 0.88 MEN1 (0.60) MEN1KMT2AMAPTUSP2ALOX15
Novaluron SCHEMBL29394806 0.88 MEN1 (0.60) MEN1KMT2AMAPTUSP2ALOX15
SCHEMBL28713610 0.86 MAPT (0.60) MEN1KMT2AMAPTUSP2ALOX15
SCHEMBL29828618 0.85 MEN1 (0.74) MEN1KMT2AMAPTUSP2ALOX15
SCHEMBL8523795 0.85 MEN1 (0.74) MEN1KMT2AMAPTUSP2ALOX15
SCHEMBL8659704 0.85 MEN1 (0.63) MEN1KMT2AMAPTUSP2ALOX15
SCHEMBL16447663 0.84 MEN1 (0.55) MEN1KMT2AMAPTUSP2ALOX15
SCHEMBL13943025 0.83 MEN1 (0.59) MEN1KMT2AMAPTUSP2ALOX15
Novaluron SCHEMBL1073389 0.82 MEN1 (0.54) MEN1KMT2AMAPTUSP2ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2780440-B1 FLOOR CLEANING FORMULATION COMPRISING AN AGENT FOR CONTROLLING INSECTS SANO BRUNOS ENTPR LTD (IL) 2018-09-19 EP disclosed
US-20180216035-A1 FLOOR CLEANING FORMULATION COMPRISING AN AGENT FOR CONTROLLING INSECTS SANO BRUNO'S ENTERPRISES LTD. (IL) 2018-08-02 US disclosed
US-20150045280-A1 FLOOR CLEANING FORMULATION COMPRISING AN AGENT FOR CONTROLLING INSECTS SANO BRUNO'S ENTERPRISES LTD. (IL) 2015-02-12 US disclosed