SCHEMBL1644824

SCHEMBL1644824

Cc1ccc(-c2nc3cc4sc(C)nc4cc3s2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.58
RAB9A P51151 7/20 0.58
NPC1 O15118 6/20 0.58
GAA P10253 6/20 0.58
KDM4E B2RXH2 6/20 0.58
APP P05067 5/20 0.58
SMN1; SMN2 Q16637 5/20 0.58
GLA P06280 3/20 0.58
TP53 P04637 2/20 0.58
SNCA P37840 1/20 0.55
ALDH1A1 P00352 4/20 0.55
HPGD P15428 2/20 0.55
HSD17B10 Q99714 2/20 0.55
PKM P14618 1/20 0.55
RORC P51449 1/20 0.49
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
POLB P06746 1/20 0.47
NFKB1 P19838 1/20 0.47
GFER P55789 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13533852 0.98 MAPT (0.56) MAPTRAB9ANPC1GAAKDM4E
SCHEMBL1645831 0.95 MAPT (0.63) MAPTRAB9ANPC1GAAKDM4E
SCHEMBL13533851 0.93 MAPT (0.61) MAPTRAB9ANPC1GAAKDM4E
SCHEMBL14205633 0.93 APP (0.65) MAPTRAB9ANPC1GAAKDM4E
SCHEMBL13533799 0.90 APP (0.63) MAPTRAB9ANPC1GAAKDM4E
SCHEMBL13286688 0.86 APP (0.49) MAPTRAB9ANPC1GAAKDM4E
SCHEMBL2622759 0.86 APP (0.49) MAPTRAB9ANPC1GAAKDM4E
SCHEMBL23954319 0.86 APP (0.58) MAPTRAB9ANPC1GAAKDM4E
SCHEMBL14193958 0.86 SMN1; SMN2 (0.58) MAPTRAB9ANPC1GAAKDM4E
SCHEMBL10068333 0.86 MAPT (0.47) MAPTRAB9ANPC1GAAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180105957-A1 PROCESS FOR MAKING COMPOSITES COMPRISING RIGID-ROD POLYMERS AND GRAPHENE NANOPARTICLES DANG THUY D (US) 2018-04-19 US disclosed
US-9850596-B2 Composites comprising rigid-rod polymers and graphene nanoparticles and process for making the same TJC Polymer Inc. (US) 2017-12-26 US disclosed
US-20150218730-A1 COMPOSITES COMPRISING RIGID-ROD POLYMERS AND GRAPHENE NANOPARTICLES AND PROCESS FOR MAKING THE SAME DANG THUY D (US) 2015-08-06 US disclosed
US-9012339-B2 Multiaxial fabric for ballistic applications E I DU PONT DE NEMOURS AND COMPANY (US) 2015-04-21 US disclosed
US-8580380-B2 Polybenzazole fiber and pyridobisimidazole fiber TOYO BOSEKI KABUSHIKI KAISHA (JP) 2013-11-12 US disclosed
US-8419989-B2 Process and apparatus for the production of yarn MAGELLAN SYSTEMS INTERNATIONAL LLC (US) 2013-04-16 US disclosed
US-8297081-B2 Staple fiber yarn, method for producing a textile article, and textile article TEIJIN ARAMID GMBH (DE) 2012-10-30 US disclosed
US-20120159699-A1 PENETRATION-RESISTANT TEXTILE FABRICS AND ARTICLES COMPRISING SAID FABRICS TEIJIN ARAMID GMBH (DE) 2012-06-28 US disclosed
US-8171569-B2 Multiaxial fabric with strain-responsive viscous liquid polymers E.I. DU PONT DE NEMOURS AND COMPANY (US) 2012-05-08 US disclosed
US-8166569-B1 Multiaxial polyethylene fabric and laminate E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-05-01 US disclosed
US-20080160247-A1 Flexible ballistic fabric and articles made therefrom DUPONT SAFETY & CONSTRUCTION, INC. 2008-07-03 US disclosed
US-20080151261-A1 Process and apparatus for online detection of surface irregularity in threadlines E. I. DU PONT DE NEMOURS AND COMPANY 2008-06-26 US disclosed
US-20080146108-A1 Coated fabrics and laminates suitable for rigid armor applications and processes for making same E. I. DU PONT DE NEMOURS AND COMPANY 2008-06-19 US disclosed
US-20080069974-A1 Liquid crystal display panel and fabricating method thereof LG.PHILIPS LCD CO., LTD. 2008-03-20 US disclosed
US-7340779-B2 Flexible spike/ballistic penetration-resistant articles E.I. DU PONT DE NEMOURS AND COMPANY (US) 2008-03-11 US disclosed
US-7262266-B2 Copolymerization of polybenzazoles and other aromatic polymers with carbon nanotubes WILLIAM MARSH RICE UNIVERSITY (US) 2007-08-28 US disclosed
US-7241709-B2 Penetration resistant life protection articles E. I DU PONT DE NEMOURS AND COMPANY (US) 2007-07-10 US disclosed
US-20070118937-A1 Copolymerization and copolymers of aromatic polymers with carbon nanotubes and products made therefrom WILLIAM MARSH RICE UNIVERSITY (US) 2007-05-24 US disclosed
US-20070105468-A1 PENETRATION RESISTANT LIFE PROTECTION ARTICLES DUPONT SAFETY & CONSTRUCTION, INC. 2007-05-10 US disclosed
US-7208109-B2 Changing the solution to nonflowable by absorbing a coagulant, then solvent extraction, for molding a solution of a liquid crystal polymer, polybenzoxazoles or polybenzothiazoles TOYO BOSEKI KABUSHIKI KAISHA (JP) 2007-04-24 US disclosed