SCHEMBL1645831

SCHEMBL1645831

Cc1ccc(-c2nc3cc4nc(C)sc4cc3s2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.63
NPC1 O15118 7/20 0.63
RAB9A P51151 7/20 0.63
SMN1; SMN2 Q16637 6/20 0.63
ALDH1A1 P00352 5/20 0.63
TP53 P04637 2/20 0.63
HPGD P15428 2/20 0.63
HSD17B10 Q99714 2/20 0.63
PKM P14618 1/20 0.63
GAA P10253 6/20 0.56
KDM4E B2RXH2 6/20 0.56
APP P05067 5/20 0.56
GLA P06280 4/20 0.56
SNCA P37840 1/20 0.54
RORC P51449 1/20 0.48
NFKB1 P19838 2/20 0.46
NFKB2 Q00653 2/20 0.46
RELA Q04206 2/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13533851 0.98 MAPT (0.61) MAPTNPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL1644824 0.95 MAPT (0.58) MAPTNPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL13533852 0.93 MAPT (0.56) MAPTNPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL13533799 0.89 APP (0.63) MAPTNPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL14205633 0.88 APP (0.65) MAPTNPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL14193953 0.87 SMN1; SMN2 (0.63) MAPTNPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL11201951 0.84 MAPT (0.60) MAPTNPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL13533863 0.83 NPC1 (0.50) MAPTNPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL2622759 0.82 APP (0.49) MAPTNPC1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL13286688 0.82 APP (0.49) MAPTNPC1RAB9ASMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9012339-B2 Multiaxial fabric for ballistic applications E I DU PONT DE NEMOURS AND COMPANY (US) 2015-04-21 US disclosed
US-8580380-B2 Polybenzazole fiber and pyridobisimidazole fiber TOYO BOSEKI KABUSHIKI KAISHA (JP) 2013-11-12 US disclosed
US-8419989-B2 Process and apparatus for the production of yarn MAGELLAN SYSTEMS INTERNATIONAL LLC (US) 2013-04-16 US disclosed
US-8297081-B2 Staple fiber yarn, method for producing a textile article, and textile article TEIJIN ARAMID GMBH (DE) 2012-10-30 US disclosed
US-20120159699-A1 PENETRATION-RESISTANT TEXTILE FABRICS AND ARTICLES COMPRISING SAID FABRICS TEIJIN ARAMID GMBH (DE) 2012-06-28 US disclosed
US-8171569-B2 Multiaxial fabric with strain-responsive viscous liquid polymers E.I. DU PONT DE NEMOURS AND COMPANY (US) 2012-05-08 US disclosed
US-8166569-B1 Multiaxial polyethylene fabric and laminate E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-05-01 US disclosed
US-20120088062-A1 MULTIAXIAL POLYETHYLENE FABRIC AND LAMINATE DUPONT SAFETY & CONSTRUCTION, INC. 2012-04-12 US disclosed
US-7900267-B2 Multiaxial fabric E.I. DU PONT DE NEMOURS AND COMPANY (US) 2011-03-08 US disclosed
US-7901529-B2 Flexible ballistic fabric and articles made therefrom E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-03-08 US disclosed
US-20080222985-A1 Composite for protection against wind and wind blown debris HANKS JEFFREY ALAN 2008-09-18 US disclosed
US-20080160247-A1 Flexible ballistic fabric and articles made therefrom DUPONT SAFETY & CONSTRUCTION, INC. 2008-07-03 US disclosed
US-20080151261-A1 Process and apparatus for online detection of surface irregularity in threadlines E. I. DU PONT DE NEMOURS AND COMPANY 2008-06-26 US disclosed
US-20080146108-A1 Coated fabrics and laminates suitable for rigid armor applications and processes for making same E. I. DU PONT DE NEMOURS AND COMPANY 2008-06-19 US disclosed
US-7340779-B2 Flexible spike/ballistic penetration-resistant articles E.I. DU PONT DE NEMOURS AND COMPANY (US) 2008-03-11 US disclosed
US-7262266-B2 Copolymerization of polybenzazoles and other aromatic polymers with carbon nanotubes WILLIAM MARSH RICE UNIVERSITY (US) 2007-08-28 US disclosed
US-7241709-B2 Penetration resistant life protection articles E. I DU PONT DE NEMOURS AND COMPANY (US) 2007-07-10 US disclosed
US-20070118937-A1 Copolymerization and copolymers of aromatic polymers with carbon nanotubes and products made therefrom WILLIAM MARSH RICE UNIVERSITY (US) 2007-05-24 US disclosed
US-20070105468-A1 PENETRATION RESISTANT LIFE PROTECTION ARTICLES DUPONT SAFETY & CONSTRUCTION, INC. 2007-05-10 US disclosed
US-7208109-B2 Changing the solution to nonflowable by absorbing a coagulant, then solvent extraction, for molding a solution of a liquid crystal polymer, polybenzoxazoles or polybenzothiazoles TOYO BOSEKI KABUSHIKI KAISHA (JP) 2007-04-24 US disclosed