SCHEMBL16448665

SCHEMBL16448665

CCC12CC3CC(C1)CC(COc1cc(F)c(C(=O)NS(=O)(=O)N4CCC4)cc1Cl)(C3)C2

nearest known ligand 0.82

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 20/20 0.82

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15535890 0.92 SCN9A (0.84) SCN9A
SCHEMBL15536841 0.90 SCN9A (1.00) SCN9A
SCHEMBL16389230 0.89 SCN9A (0.96) SCN9A
SCHEMBL15549240 0.88 SCN9A (0.74) SCN9A
SCHEMBL16348596 0.83 SCN9A (1.00) SCN9A
SCHEMBL16389235 0.83 SCN9A (1.00) SCN9A
SCHEMBL15536324 0.82 SCN9A (1.00) SCN9A
SCHEMBL16448664 0.81 SCN9A (0.61) SCN9A
SCHEMBL16448513 0.81 SCN9A (1.00) SCN9A
SCHEMBL15535592 0.81 SCN9A (1.00) SCN9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8952169-B2 N-substituted benzamides and methods of use thereof XENON PHARMACEUTICALS INC. (CA) 2015-02-10 US disclosed