Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 11/20 | 0.42 |
| ▸ | PPARG | P37231 | 10/20 | 0.42 |
| ▸ | PPARD | Q03181 | 10/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28073790 | 1.00 | FFAR1 (0.42) | FFAR1PPARGPPARDCYP3A4MAOA | |
| SCHEMBL29288527 | 0.79 | TMEM97 (0.41) | FFAR1PPARGPPARDCYP3A4MAOA | |
| SCHEMBL9979676 | 0.78 | CYP3A4 (0.40) | FFAR1PPARGPPARDCYP3A4MAOA | |
| SCHEMBL204645 | 0.78 | PPARG (0.60) | FFAR1PPARGPPARDPPARA | |
| SCHEMBL9979637 | 0.78 | PPARG (0.60) | FFAR1PPARGPPARDPPARA | |
| SCHEMBL3003128 | 0.78 | PPARG (0.60) | FFAR1PPARGPPARDPPARA | |
| SCHEMBL13524014 | 0.77 | PPARG (0.46) | FFAR1PPARGPPARDCYP3A4MAOA | |
| SCHEMBL435248 | 0.76 | FFAR1 (0.53) | FFAR1PPARGPPARDPPARA | |
| SCHEMBL9277990 | 0.76 | FFAR1 (0.53) | FFAR1PPARGPPARDPPARA | |
| SCHEMBL15791414 | 0.76 | PPARG (0.46) | FFAR1PPARGPPARDCYP3A4MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8952185-B2 | Production method of optically active dihydrobenzofuran derivative | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2015-02-10 | — | — | US | disclosed |