Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16448943 | 0.90 | ACHE (0.51) | ACHEBCHEHCAR2KDM4EATM | |
| SCHEMBL16448942 | 0.90 | HCAR2 (0.53) | ACHEBCHEHCAR2KDM4EKMT2A | |
| Hydrochloric Acid SCHEMBL16038209 | 0.90 | KMT2A (0.49) | BCHEKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL16448946 | 0.89 | BCHE (0.56) | ACHEBCHEHCAR2KDM4EKMT2A | |
| Hydrochloric Acid SCHEMBL16037851 | 0.88 | KMT2A (0.46) | BCHEKDM4EKMT2AMEN1ATM | |
| SCHEMBL16448948 | 0.87 | ATM (0.62) | ACHEHCAR2KDM4EKMT2AMEN1 | |
| SCHEMBL16435308 | 0.87 | KMT2A (0.44) | BCHEKDM4EKMT2AMEN1ATM | |
| SCHEMBL15171911 | 0.87 | KMT2A (0.44) | HCAR2KDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL16090954 | 0.87 | KMT2A (0.44) | HCAR2KDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL16448941 | 0.86 | HCAR2 (0.57) | ACHEBCHEHCAR2KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8952006-B2 | Morpholinoalkyl fumarate compounds, pharmaceutical compositions, and methods of use | XENOPORT, INC. (US) | 2015-02-10 | — | — | US | disclosed |