Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 2/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | THRA | P10827 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16448950 | 0.98 | HCAR2 (0.57) | HCAR2ATMACHEBCHETHRA | |
| SCHEMBL16448944 | 0.95 | HCAR2 (0.57) | HCAR2ATMACHEBCHETHRA | |
| SCHEMBL16448947 | 0.95 | ATM (0.61) | HCAR2ATMACHEBCHETHRA | |
| SCHEMBL16448949 | 0.93 | ATM (0.51) | HCAR2ATMACHEBCHEHRH3 | |
| SCHEMBL16448941 | 0.93 | HCAR2 (0.57) | HCAR2ATMACHEBCHETHRA | |
| SCHEMBL16448951 | 0.91 | ATM (0.62) | HCAR2ATMACHEBCHETHRA | |
| SCHEMBL16448946 | 0.90 | BCHE (0.56) | HCAR2ATMACHEBCHEHRH3 | |
| SCHEMBL15171910 | 0.88 | ACHE (0.49) | HCAR2ATMACHEBCHEHRH3 | |
| SCHEMBL15171909 | 0.88 | ACHE (0.49) | HCAR2ATMACHEBCHEHRH3 | |
| SCHEMBL16448948 | 0.88 | ATM (0.62) | HCAR2ATMACHETHRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8952006-B2 | Morpholinoalkyl fumarate compounds, pharmaceutical compositions, and methods of use | XENOPORT, INC. (US) | 2015-02-10 | — | — | US | disclosed |