Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8641566 | 0.79 | — | — | |
| SCHEMBL9618133 | 0.79 | HCAR2 (0.32) | — | |
| SCHEMBL6652488 | 0.77 | TSHR (0.40) | TSHRTP53EGLN1EGLN3 | |
| Maleic Acid SCHEMBL31231832 | 0.59 | — | — | |
| Maleic Acid SCHEMBL27583410 | 0.57 | TSHR (0.82) | TSHRTP53EGLN1EGLN3 | |
| Maleic Acid SCHEMBL28275189 | 0.57 | TSHR (0.82) | TSHRTP53EGLN1EGLN3 | |
| SCHEMBL31287523 | 0.56 | TSHR (0.38) | TSHRTP53EGLN1EGLN3 | |
| Fumaric Acid SCHEMBL6875 | 0.56 | TSHR (1.00) | TSHRTP53EGLN1EGLN3 | |
| Maleic Acid SCHEMBL20487516 | 0.56 | TSHR (1.00) | TSHRTP53EGLN1EGLN3 | |
| Fumaric Acid SCHEMBL3998225 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2303252-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC SYNDROME AND INSULIN RESISTANCE | Jungbauer, Alois (AT) | 2011-04-06 | — | — | EP | disclosed |
| WO-2009137859-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC SYNDROME AND INSULIN RESISTANCE | JUNGBAUER ALOIS (AT) | 2009-11-19 | — | — | WO | disclosed |