Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.51 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.51 |
| ▸ | MKNK1 | Q9BUB5 | 12/20 | 0.50 |
| ▸ | MKNK2 | Q9HBH9 | 12/20 | 0.50 |
| ▸ | DNM2 | P50570 | 2/20 | 0.50 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL657460 | 0.78 | MRGPRX1 (0.57) | HTR7MRGPRX1DNM2 | |
| SCHEMBL19477219 | 0.77 | DNM2 (0.71) | DNM2 | |
| SCHEMBL15584142 | 0.76 | FLT3 (0.56) | MKNK1MKNK2FLT3 | |
| SCHEMBL1401613 | 0.75 | DNM2 (0.78) | DNM2KCNH3 | |
| SCHEMBL4906864 | 0.75 | MKNK1 (0.71) | MKNK1MKNK2KCNH3 | |
| SCHEMBL28133994 | 0.74 | HPGD (0.59) | MKNK1MKNK2KCNH3 | |
| SCHEMBL28661902 | 0.74 | DNM2 (0.64) | DNM2 | |
| SCHEMBL2021808 | 0.74 | MKNK1 (0.47) | HTR7MKNK1MKNK2FLT3 | |
| SCHEMBL2023032 | 0.73 | MKNK1 (0.58) | MKNK1MKNK2FLT3 | |
| SCHEMBL15584085 | 0.72 | FLT3 (0.58) | MKNK1MKNK2FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9145415-B2 | Nitrogen-containing heterocyclic compound or salt thereof | FUJIFILM CORPORATION (JP) | 2015-09-29 | — | — | US | disclosed |
| US-20150045339-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND OR SALT THEREOF | FUJIFILM CORPORATION (JP) | 2015-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150045339-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND OR SALT THEREOF | FLT3, NPM1, ABL1 | HTR7 4624/4885MRGPRX1 2895/4885MKNK1 356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.