SCHEMBL16450313

SCHEMBL16450313

CCC(C)c1ccc(N(c2ccc(C)cc2)c2ccc(-c3ccc(N(c4ccc(-c5ccc(C(CC(C)C)c6ccc(C)cc6)cc5)cc4)c4ccc(C(C)CC)cc4)cc3)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GRIA4 P48058 1/20 0.38
ACHE P22303 1/20 0.36
TSHR P16473 2/20 0.34
CYP2C9 P11712 1/20 0.34
ALDH1A1 P00352 1/20 0.34
CTSL P07711 1/20 0.34
CTSB P07858 1/20 0.34
CTSS P25774 1/20 0.34
CTSK P43235 1/20 0.34
GPR88 Q9GZN0 1/20 0.34
CYP17A1 P05093 1/20 0.33
DHODH Q02127 1/20 0.32
FFAR1 O14842 1/20 0.32
STAT3 P40763 1/20 0.31
HRH3 Q9Y5N1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14200065 0.89 GRIA4 (0.45) GRIA4ACHETSHRCYP2C9ALDH1A1
SCHEMBL12016670 0.89 GRIA4 (0.45) GRIA4ACHETSHRCYP2C9ALDH1A1
SCHEMBL14169208 0.89 GRIA4 (0.45) GRIA4ACHETSHRCYP2C9ALDH1A1
SCHEMBL14592726 0.89 GRIA4 (0.45) GRIA4ACHETSHRCYP2C9ALDH1A1
SCHEMBL9631348 0.87 CHRNA7 (0.38) ACHETSHRALDH1A1
SCHEMBL13897757 0.86 GRIA4 (0.41) GRIA4ACHETSHRCYP2C9ALDH1A1
SCHEMBL2607396 0.84 CYP2C9 (0.43) GRIA4ACHETSHRCYP2C9ALDH1A1
SCHEMBL13883743 0.84 CYP2C9 (0.43) GRIA4ACHETSHRCYP2C9ALDH1A1
SCHEMBL12619660 0.83 GRIA4 (0.41) GRIA4ACHETSHRCYP2C9ALDH1A1
SCHEMBL15458072 0.81 CYP2C19 (0.42) ACHETSHRCYP2C9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150041797-A1 POLYMER AND ORGANIC ELECTROLUMINESCENT ELEMENT MITSUBISHI CHEMICAL CORPORATION (JP) 2015-02-12 US disclosed