SCHEMBL9631348

SCHEMBL9631348

Cc1ccc(N(c2ccc(C)cc2)c2ccc(C(CC(C)C)c3ccc(N(c4ccc(C)cc4)c4ccc(C)cc4)cc3)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CHRNA7 P36544 1/20 0.38
ACHE P22303 1/20 0.37
ALDH1A1 P00352 1/20 0.37
TSHR P16473 1/20 0.37
CYP2C19 P33261 1/20 0.36
CNR2 P34972 2/20 0.34
CNR1 P21554 1/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
ALOX5 P09917 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
CYP19A1 P11511 1/20 0.33
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32
CA7 P43166 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16450313 0.87 GRIA4 (0.38) ACHEALDH1A1TSHR
SCHEMBL11982696 0.84 CYP2C19 (0.30) CYP2C19
SCHEMBL10631859 0.82 CHRNA7 (0.41) CHRNA7ACHEALDH1A1TSHRCYP2C19
SCHEMBL12367721 0.77 CHRNA7 (0.44) CHRNA7ACHEALDH1A1TSHRCYP2C19
SCHEMBL9630229 0.77 CHRNA7 (0.44) CHRNA7ACHEALDH1A1TSHRCYP2C19
SCHEMBL13234662 0.77 CHRNA7 (0.44) CHRNA7ACHEALDH1A1TSHRCYP2C19
SCHEMBL20386671 0.77 CHRNA7 (0.44) CHRNA7ACHEALDH1A1TSHRCYP2C19
SCHEMBL20657058 0.77 HTR2A (0.45) CHRNA7ACHEALDH1A1TSHRCYP2C19
SCHEMBL2607396 0.76 CYP2C9 (0.43) CHRNA7ACHEALDH1A1TSHRMEN1
SCHEMBL13883743 0.76 CYP2C9 (0.43) CHRNA7ACHEALDH1A1TSHRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4127412-A BIS(AMINOARYL)ALKANES EASTMAN KODAK COMPANY (US) 1978-11-28 US claimed
US-5124218-A Photoconductor element for making multiple copies and process for using same EASTMAN KODAK COMPANY (US) 1992-06-23 US disclosed
US-4539282-A SENSITIZED ZINC OXIDE, POLYCARBONATE BINDER AND AROMATIC DIAMINE TOMOEGAWA PAPER MANUFACTURING COMPANY LIMITED (JP) 1985-09-03 US disclosed
EP-0115198-A1 Electrophotographic photoconductive elements TOMOEGAWA PAPER MANUFACTURING COMPANY LIMITED (JP) 1984-08-08 EP disclosed
US-4127412-A BIS(AMINOARYL)ALKANES EASTMAN KODAK COMPANY (US) 1978-11-28 US disclosed