Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.56 |
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.52 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16451215 | 0.92 | MAPT (0.60) | MAPTTSHRKMT2AMEN1POLB | |
| SCHEMBL1630322 | 0.90 | KMT2A (0.63) | TSHRKMT2AMEN1POLBSMN1; SMN2 | |
| SCHEMBL16451213 | 0.89 | SMN1; SMN2 (0.61) | MAPTTSHRKMT2AMEN1POLB | |
| SCHEMBL16451216 | 0.86 | SMN1; SMN2 (0.58) | MAPTTSHRKMT2AMEN1POLB | |
| SCHEMBL17013407 | 0.85 | KCNK3 (0.69) | MAPTKMT2AMEN1POLBRXFP1 | |
| SCHEMBL24193768 | 0.84 | KMT2A (0.57) | KMT2AMEN1POLBSMN1; SMN2RAB9A | |
| SCHEMBL13657050 | 0.83 | KMT2A (0.60) | KMT2AMEN1POLBSMN1; SMN2RAB9A | |
| SCHEMBL16451217 | 0.83 | SMN1; SMN2 (0.58) | MAPTTSHRKMT2AMEN1POLB | |
| SCHEMBL22822623 | 0.82 | MAPT (0.65) | MAPTTSHRKMT2AMEN1POLB | |
| SCHEMBL31689731 | 0.82 | MAPT (0.65) | MAPTTSHRKMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150044927-A1 | FURAN BASED POLYAMIDES | E I DU PONT DE NEMOURS AND COMPANY (US) | 2015-02-12 | — | — | US | disclosed |
| US-20150044927-A1 | FURAN BASED POLYAMIDES | E I DU PONT DE NEMOURS AND COMPANY (US) | 2015-02-12 | — | — | US | disclosed |