Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.58 |
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 7/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16451213 | 0.88 | SMN1; SMN2 (0.61) | SMN1; SMN2MAPTTSHRRAB9AHTT | |
| SCHEMBL16451216 | 0.86 | SMN1; SMN2 (0.58) | SMN1; SMN2MAPTTSHRRAB9AHTT | |
| SCHEMBL16451214 | 0.83 | MAPT (0.64) | SMN1; SMN2MAPTTSHRRAB9AHTT | |
| SCHEMBL16451215 | 0.83 | MAPT (0.60) | SMN1; SMN2MAPTTSHRRAB9AHTT | |
| SCHEMBL17899811 | 0.74 | SMN1; SMN2 (1.00) | SMN1; SMN2MAPTTSHRRAB9AHTT | |
| SCHEMBL22822623 | 0.73 | MAPT (0.65) | SMN1; SMN2MAPTTSHRRAB9AHTT | |
| SCHEMBL31689731 | 0.73 | MAPT (0.65) | SMN1; SMN2MAPTTSHRRAB9AHTT | |
| SCHEMBL1487964 | 0.72 | ALDH1A1 (0.66) | SMN1; SMN2MAPTRAB9AALDH1A1MEN1 | |
| SCHEMBL17013407 | 0.72 | KCNK3 (0.69) | MAPTMEN1KMT2APOLBPKM | |
| SCHEMBL24193768 | 0.71 | KMT2A (0.57) | SMN1; SMN2RAB9AALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150044927-A1 | FURAN BASED POLYAMIDES | E I DU PONT DE NEMOURS AND COMPANY (US) | 2015-02-12 | — | — | US | disclosed |