Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 15/20 | 0.42 |
| ▸ | RIPK3 | Q9Y572 | 2/20 | 0.41 |
| ▸ | ABL1 | P00519 | 2/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1645879 | 0.91 | RIPK3 (0.47) | MAPK14RIPK3ABL1MAPK10GSK3B | |
| SCHEMBL16105262 | 0.87 | CSNK1D (0.48) | MAPK14RIPK3ABL1MAPK10GSK3B | |
| SCHEMBL1647509 | 0.86 | RIPK3 (0.46) | MAPK14RIPK3ABL1MAPK10GSK3B | |
| SCHEMBL1645057 | 0.86 | MAPK14 (0.43) | MAPK14ABL1MAPK10GSK3BCSNK1D | |
| SCHEMBL1649098 | 0.81 | ABL1 (0.41) | MAPK14ABL1GSK3BCSNK1DBRAF | |
| SCHEMBL16105479 | 0.81 | MAPK14 (0.47) | MAPK14RIPK3ABL1MAPK10GSK3B | |
| SCHEMBL1645150 | 0.80 | CSNK1D (0.40) | MAPK14ABL1GSK3BCSNK1DBRAF | |
| SCHEMBL16105465 | 0.80 | CSNK1D (0.58) | MAPK14ABL1MAPK10CSNK1D | |
| SCHEMBL16105381 | 0.80 | TGFBR1 (0.42) | MAPK14RIPK3ABL1MAPK10GSK3B | |
| SCHEMBL1646713 | 0.79 | CSNK1D (0.44) | MAPK14ABL1CSNK1DBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2784071-A1 | 3-PHENYL-4-PYRI(MI)DINYL-1H-PYRAZOLES AND THEIR USE AS FUNGICIDES | Bayer CropScience AG (DE) | 2014-10-01 | — | — | EP | disclosed |
| EP-2784073-A1 | 3-PHENYL-4-PYRI(MI)DINYL-1H-PYRAZOLES AND THEIR USE AS FUNGICIDES | Bayer CropScience AG (DE) | 2014-10-01 | — | — | EP | disclosed |
| EP-2784070-A1 | 3-PHENYL-4-PYRI(MI)DINYL-1H-PYRAZOLES AND THEIR USE AS FUNGICIDES | Bayer CropScience AG (DE) | 2014-10-01 | — | — | EP | disclosed |
| EP-2784072-A1 | 3-PHENYL-4-PYRI(MI)DINYL-1H-PYRAZOLES AND THEIR USE AS FUNGICIDES | Bayer CropScience AG (DE) | 2014-10-01 | — | — | EP | disclosed |
| EP-2308866-A1 | Phenylpyri(mi)dinylpyrazoles and their use as fungicides | Bayer CropScience AG (DE) | 2011-04-13 | — | — | EP | disclosed |