Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 4/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA4 | P22748 | 2/20 | 0.54 |
| ▸ | CA6 | P23280 | 2/20 | 0.54 |
| ▸ | CA5A | P35218 | 2/20 | 0.54 |
| ▸ | CA7 | P43166 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.54 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.54 |
| ▸ | TYR | P14679 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 2/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | APP | P05067 | 2/20 | 0.49 |
| ▸ | YWHAG | P61981 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15153035 | 0.89 | YWHAG (0.62) | METCA12CA1CA4CA6 | |
| SCHEMBL19047031 | 0.86 | APP (0.59) | METCA12CA1CA4CA6 | |
| SCHEMBL12246766 | 0.85 | APP (0.67) | METCA12CA1CA4CA6 | |
| SCHEMBL8985470 | 0.83 | MET (0.55) | METCA12CA1CA4CA6 | |
| SCHEMBL6025448 | 0.82 | TDP1 (0.66) | ESR1ESR2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL419309 | 0.82 | ESR1 (0.64) | METCA12CA1CA4CA6 | |
| SCHEMBL19047033 | 0.82 | MET (0.59) | METCA12CA1CA4CA6 | |
| SCHEMBL15164356 | 0.82 | MET (0.59) | METCA12CA1CA4CA6 | |
| SCHEMBL15164333 | 0.81 | APP (0.54) | METCA12CA1CA4CA6 | |
| SCHEMBL19047040 | 0.81 | YWHAG (0.58) | METCA12CA1CA4CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150045451-A1 | POLYMERIC BIOMATERIALS DERIVED FROM MONOMERS COMPRISING HYDROXYACIDS AND PHENOL COMPOUNDS AND THEIR MEDICAL USES | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2015-02-12 | — | — | US | disclosed |